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    2009  AIDS PATIENT CARE and STDs       
    Carmina R. Fumaz, Ph.D., Jose A. Muñoz-Moreno, M.S., María José Ferrer, M.S., Eugenia Negredo, Ph.D., Nuria Pérez-Álvarez, M.S., Antoni Tarrats, Ph.D., and Bonaventura Clotet, Ph.D. 
    Low Levels of Adherence to Antiretroviral Therapy in HIV-1–Infected Women with Menstrual Disorders 

    2009  AIDS Res Hum Retroviruses       
    E. Negredo, J. Puig, D. Aldea, M. Medina, C. Estany, N. Pérez-Alvarez, CR. Fumaz, J. Muñoz-Moreno, C. Higueras, V. Gonzalez-Mestre, B. Clotet 
    Four-year safety with polyacrylamide hydrogel to correct antiretroviral-related facial lipoatrophy 

    2009  CID       
    Athe M. N. Tsibris, Roger Paredes, Amy Chadburn, Zhaohui Su, Timothy J. Henrich, Amy Krambrink, Michael D. Hughes, Judith A. Aberg, Judith S. Currier, Karen Tashima, Catherine Godfrey, Wayne Greaves, Charles Flexner, Paul R. Skolnik, Timothy J. Wilkin, Roy M. Gulick and Daniel R. Kuritzkes 
    Lymphoma Diagnosis and Plasma Epstein-Barr Virus Load during Vicriviroc Therapy: Results of the AIDS Clinical Trials Group A5211 

    2009  Current HIV Research       
    JM Llibre 
    The Changing Face of HIV/AIDS in Treated Patients 

    2009  HIV Clinical Trials       
    José Ramon Santos, José Moltó, Josep Maria Llibre, Núria Pérez, Mari Carmen Capitán, Cristina Miranda, Bonaventura Clotet 
    Unboosted Atazanavir Plus co-formulated Lamivudine/Abacavir as a Ritonavir-Sparing Simplification Strategy in Routine Clinical Practice  

    2009  HIV Clinical Trials       
    José Ramón Santos, José Moltó, Josep Maria Llibre, Nuria Pérez, Mari Carmen Capitán, Cristina Miranda and Bonaventura Clotet 
    Unboosted Atazanavir Plus Co-formulated Lamivudine/Abacavir as a Ritonavir-Sparing Simplification Strategy in Routine Clinical Practice 

    2009  Journal of Antimicrobial Chemotherapy       
    José Moltó, Josep Maria Llibre, Esteban Ribera, Carlos Mínguez, Jesús Sánchez del Río, Enric Pedrol, Gabriel Vallecillo, Samandhy Cedeño, Marta Valle, Cristina Miranda, Eugenia Negredo and Bonaventura Clotet on behalf of the SQV-HEP Study Group. 
    Saquinavir exposure in HIV-infected patients with chronic viral hepatitis 

    2009  Journal of Virology       
    Roger Paredes, Manish Sagar, Vincent C. Marconi, Rebecca Hoh, Jeffrey N. Martin, Neil T. Parkin, Christos J. Petropoulos, Steven G. Deeks, and Daniel R. Kuritzkes 
    In Vivo Fitness Cost of the M184V Mutation in Multidrug-Resistant Human Inmunodeficiency virus Type 1 in the Absence of Lamiduvine 

    2008         
    Jose Molto, Marta Valle, Cristina Miranda, Samandhy Cedeno, Jose Miranda, Jose Ramon Santos, Eugenia Negredo, Josep Vilaro, Joan Costa, Bonaventura Clotet  
    Once or Twice Daily Dosing of Nevirapine in HIV-Infected Adults: A Population Pharmacokinetics Approach 

    2008  AIDS Care, Vol. 20, No. 7, August 2008, 796 - 805.       
    Fumaz CR, Muñoz-Moreno JA, Moltó J, Ferrer MJ, López-Blázquez R, Negredo E, Paredes R, Gómez G, Clotet B. 
    Sustained antiretroviral treatment adherence in survivors of the pre-HAART era: attitudes and beliefs. AIDS Care 2008;20(7):796-805.  

    2008  AIDS RESEARCH AND HUMAN RETROVIRUSES Volum 24, Número 10, 2008       
    Jose A. Muñoz-Moreno, Carmina R. Fumaz, Maria J. Ferrer, Anna Prats, Eugènia Negredo, Maite Garolera, Núria Pérez-Álvarez, José Moltó, Guadalupe Gómez i Bonaventura Clotet 
    Nadir CD4 Cell Count Predicts Neurocognitive Impairment in HIV-Infected Patients  

    2008  AIDS RESEARCH AND HUMAN RETROVIRUSES, Volume 24, Number 5, 2008       
    Laila Darwich, Anna Esteve, Lídia Ruiz, Roger Paredes, Rocío Bellido, Cecília Cabrera, Joan Romeu, Margarita Bofill, Bonaventura Clotet, and Javier Martínez-Picado 
    Drug-Resistance Mutations Number and K70R or T215Y/F Substitutions Predict Treatment Resumption during Guided Treatment Interruptions 

    2008  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Nov. 2008       
    José Moltó, José R. Santos, Núria Pérez-Álvarez, Samandhy Cedeño, Cristina Miranda, Saye Khoo, Laura Else, Josep Maria Llibre, Marta Valle and Bonaventura Clotet 
    Darunavir Inhibitory Quotient Predicts the 48-Week Virological Response to Darunavir-Based Salvage Therapy in Human Immunodeficiency Virus-Infected Protease Inhibitor-Experienced Patients 

    2008  Clinical Pharmacokinetics       
    José Moltó, Manuel José Barbanoj, Cristina Miranda, Asunción Blanco, José Ramón Santos, Eugenia Negredo, Joan Costa, Pere Domingo, Bonaventura Clotet, Marta Valle 
    Simultaneous Population Pharmacokinetic Model for Lopinavir and Ritonavir in HIV-Infected Adults 

    2008  Enferm Infecc Microbiol Clin. 2008;26 Supl 12:17-22       
    Josep M. Llibre y Javier Martínez-Picado 
    Potencial de los inhibidores de la integrasa para deplecionar los reservorios o para impedir que se rellenen 

    2008  HIV Medicine       
    JM Llibre, A Bonjoch, J Iribarren, MJ Galindo, E Negredo, P Domingo, N Pérez-Álvarez, J Martínez-Picado, J Schapiro, B Clotet and the HIV Conference Call study group 
    Targeting only reverse transcriptase with zidovudine/lamivudine/abacavir plus tenofovir in HIV-1-infected patients with multidrug-resistant virus: a multicentre pilot study 

    2008  JAIDS (J Acquir Immune Defic Syndr)       
    Vincent Marconi, MD, Sebastian Bonhoeffer, PhD, Roger Paredes, MD, Jing Lu, MD, Rebecca Hoh, RD, Jeffery N. Martin, MPH, Steven G. Deeks, MD and Daniel R. Kuritzkes, MD 
    Viral Dynamics and In Vivo Fitness of HIV-1 in the Presence and Absence of Enfuvirtide 

    2008  Journal of Antimicrobial Chemotherapy       
    J. M. Llibre, J. R. Santos, T. Puig, J. Moltó, L. Ruiz, R. Paredes and B. Clotet 
    Prevalence of etravirine-associated mutations in clinical samples with resistance to nevirapine and efavirenz 

    2008  Journal of Antimicrobial Chemotherapy       
    Josep M. Llibre, Pere Domingo, Miguel A. del Pozo, Celia Miralles, Maria J. Galindo, Isabel Viciana, Santiago Moreno, Jonathan M. Schapiro and Bonaventura Clotet 
    Long-distance interactive expert advice in highly treatment-experienced HIV-infected patients 

    2008  JVI       
    Roger Paredes, Manish Sagar, Vincent C. Marconi, Rebecca Hoh, Jeffrey N. Martin, Neil T. Parkin, Christos J. Petropoulos, Steven G. Deeks, Daniel R. Kuritzkes 
    In Vivo Fitness Cost of the M184V Mutation in Multidrug-Resistant HIV-1 in the Absence of Lamivudine 

    2007  AIDS care; 19 (1): 138-145. (IF: 2.093).       
    Fumaz, CR.; Munoz-Moreno, JA.; Ballesteros, AL.; Paredes, R.; Ferrer, MJ.; Salas, A.; Fuster, D.; Masmitja, E.; Perez-Alvarez, N.; Gomez, G.; Tural, C.; Clotet, B. 
    Influence of the type of pegylated interferon on the onset of depressive and neuropsichiatric symptoms in HIV-HCV coinfected patients. 

    2007  AIDS Cyber J; 10 (6).       
    Muñoz-Moreno, JA. 
    Alteraciones neurocognitivas asociadas a las interrupciones del tratamiento antiretroviral en la infección por el VIH. 

    2007  AIDS Patient Care STDS; 21 (8): 533-543. (IF: 2.007)       
    Reynes, J.; Arasteh, K.; Clotet, B.; Cohen, C.; Cooper, D.; Delfraissy, JF.; Eron, JJ.; Henry, K.; Katlama, C.; Kuritzkes, DR.; Lalezari, JP.; Lange, J.; Lazzarin, A.; Montaner, JS.; Nelson, M.; Stellbrink, HJ.; Trottier, B.; Walmsley, SL:; Buss, NE.; Demasi, R.; Chung, J.; Donatacci, L.; Guimaraes, D.; Rowell, L.; Valentine, A.; Wilkinson, M.; Salgo, MP. 
    TORO: Ninety-Six-Week virologic and immunologic response and safety evaluation of Enfuvirtide with optimized background of antiretrovirals. 

    2007  AIDS Res Hum Retroviruses; 23 (10): 1166-1175.       
    Muñoz-Moreno, JA.; Fumaz, CR.; Ferrer, MJ.; Tuldrà, A.; Rovira, T.; Viladrich, C.; Bayés, R.; Burger, DM.; Negredo, E.; Clotet, B.; SERAD Validation Team. 
    Assessing self-reported adherence to HIV therapy by questionnaire: the SERAD (Self-reported adherence) Study. 

    2007  AIDS Research and Human Retroviruses; 23 (8): 961-967. (IF: 2.513)       
    Sirera, G.; Videla, S.; Lopez-Blazquez, R.; Llatjos, M.; Tarrats, A.; Castella, E.; Grane, N.; Alcalde, C.; Tural, C.; Rey-Joly, C.; Clotet, B. 
    Evolution of cervical cytologic changes among hiv-infected women with normal cytology in the HAART era. 

    2007  AIDS. 21(2):169-178       
    Ruiz L, Paredes R, Gomez G, Romeu J, Domingo P, Perez-Alvarez N, Tambussi G, Llibre JM, Martinez-Picado J, Vidal F, Fumaz CR, Clotet B; The TIBET Study Group.  
    Antiretroviral therapy interruption guided by CD4 cell counts and plasma HIV-1 RNA levels in chronically HIV-1-infected patients. 

    2007  AIDS: 21 (6): 721-732. (IF: 5.632)       
    Cozzi-Lepri, A.; Philips, AN.; Ruiz, L.; Clotet, B.; Loveday, C.; Kjaer, J.; Mens, H.; Clumeck, N.; Viksna, L.; Antunes, F.; Machala, L.; Lundgren, JD. 
    Evolution of drug resistance in HIV-infected patients remaining on a virologically failing combination antiretroviral therapy regimen. 

    2007  AIDS; 21 (10): 1273-1281. (IF: 5.632)       
    Nelson, MR.; Katlama, C.; Montaner, JS.; Cooper, DA.; Gazzard, B.; Clotet, B.; Lazzarin, A.; Schewe, K.; Lange, J.; Wyatt, C.; Curtis, S.; Chen, S.; Smith, S.; Bischofberger, S.; Rooney, JF. 
    The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years. 

    2007  AIDS; 21 (12): 1555-1559. (IF: 5.632)       
    Dore, GJ.; Torriani, FJ.; Rodriguez-Torres, M.; Bräu, N.; Sulkowski, M.; Lamoglia, RS.; Tural, C.; Clumeck, N.; Nelson, MR.; Mendes-Correa, MC.; Codofsky, EW.; Dieterich, DT.; Yetzer, E.; Lissen, E.; Cooper, DA. 
    Baseline factors prognostic od sustained virological response in patients with HIV-hepatitis C virus c-infection. 

    2007  AIDS; 21 (3): 367-369 (IF: 5.632)       
    Martinez, E.; Arnaiz, JA.; Podzamczer, D.; Dalmau, D.; Ribera, E.; Domingo, P.; Knobel, H.; Leyes, M.; Pedrol, E.; Force, L.; de Lazzari, E.; Gatell, JM. for the NEFA Study Team. Participating centre and investigator: Llibre, JM. 
    Three-year Follow-up of protease inhibitor-based regimen simplification in HIV-infected patients. 

    2007  AIDS; 21 (6): 657-663. (IF: 5.632)       
    Negredo, E.; Estany, C.; Martínez, E.; Clotet, B. 
    Therapeutic Management of Bone Demineralisation in the HIV-infected population. 

    2007  AIDS; 21 (6): 657-663. (IF: 5.632)       
    Negredo, E.; Martínez, E.; Cinquegrana, D.; Estany, C.; Clotet, B. 
    Therapeutic management of bone demineralization in the HIV-infected population. 

    2007  Ann Intern Med; 146: 574-579.       
    Gavalda, J.; Len, O.; Miró, JM.; Muñoz, P.; Montejo, M.; Alarcón, A.; de la Torre-Cisneros, J.; Peña, C.; Martinez-la Casa, X.; Sarria, C.; Bou, G.; Aguado, JM.; Navas, E.; Romeu, J.; Marco, F.; Torres, C.; Tornos, P.; Planes, A.; Falcó, V.; Almirante, B.; Pahissa, A. 
    Treatment of Enterococcus faecalis endocarditis with ampicillin plus ceftriaxone. 

    2007  Antiviral Therapy (en prensa)       
    Negredo, E. et al. 
    Partial immunological and mithocondrial recovery after reducing Didanosine doses in patients receiving Didanosine and Tenofovir-Based regimens. 

    2007  Antiviral Therapy; 12: S680. (IF: 4.98)       
    Llibre, JM.; Bonjoch, A.; Iribarren, JA.; Galindo, MJ.; Martinez-Picado, X.; Arazo, P.; Santos, JR.; Domingo, P.; Clotet, B. 
    Viral evolution in HIV-1 reverse transcriptase in patients receiving a holding regimen with Trizivir and tenofovir with persistent viral replication. 

    2007  Antiviral Therapy; 12: S74. (IF: 4.98)       
    Llibre, JM.; Santos, JR.; Puig, T.; Moltó, J.; Ruiz, L.; Clotet, B. 
    Prevalence of etravirine-associated mutations in clinical samples with resistance to nevirapine and efavirenz. 

    2007  Area clínica; 15 (57): 83-93       
    Clotet, B. 
    Revisión clínica de Raltegravir (MK-0518). El primero en una nueva clase terapéutica para VIH. 

    2007  Br J Clin Pharmacol; 63 (6): 715-721. (IF: 2.718)       
    Molto, J.; Blanco, A.; Miranda, C.; Miranda, J.; Puig, J.; Valle, M.; Delavarga, M.; Fumaz, CR.; Barbanoj, MJ.; Clotet, B. 
    Variability in non-nucleoside reverse transcriptase and protease inhibitors concentrations among HIV-infected adults in routine clinical practice. 

    2007  Clin Exp Immunol 147:189-96       
    Pauls E, Senserrich J, Bofill M, Clotet B, Este JA.  
    Induction of interleukins IL-6 and IL-8 by siRNA. 

    2007  Clin Pharmacokinetic; 46 (1): 85-92. (IF: 4.115)       
    Moltó, J.; Valle, M.; Blanco, A.; Negredo, E.; Delavarga, M.; Miranda, C.; Miranda, J.; Domingo, P.; Vilaró, J.; Tural, C.; Costa, J.; Barbanoj, MJ.; Clotet, B. 
    Lopinavir/ritonavir pharmacokinetics in HIV and hepatitis C virus co.infected patients without liver function impairment: influence of liver fibrosis. 

    2007  Curr Opin HIV AIDS; 2: 145-149.       
    Clotet, B.; Paredes, R. 
    Clinical approach to drug resistance interpretation: expert advice. 

    2007  Enfermedades infecciosas y Microbiol Clin; 25: 131-142.       
    Ribera, E.; Moreno, S.; Viciana, P.; Echevarria, S.; Flores, J.; Francés, A. et al y participantes en el documento (entre ellos JM Llibre) 
    Recomendaciones españolas sobre el uso adecuado de enfuvirtida. 

    2007  Enfermedades infecciosas y Microbiología Clínica; 25 (2): 98-107       
    Llibre, JM.; Casado, MA.; Sanchez de la Rosa, R.; Perez-Elias, MJ.; Santos, JR.; Miralles, C.; Martinez, E.; Domingo, P.; Alvarez, ML.; Moreno, S. 
    Costes de la toxicidad asociada a los análogos de nucleósidos inhibidores de la transcriptasa inversa en pacientes con infección por el VIH-1. 

    2007  Hepatitis Hoy; 3 (3):86-90       
    Tural, C.; Jou, A.; Sirera, G.; Salas, A.; Planas, R.; Clotet, B. 
    ¿Es diferente la cinética del virus de la Hepatitis C en los pacientes infectados por el virus de la inmunodeficiencia humana? 

    2007  Hepatology. (IF: 10.446)       
    Nattermann, J.; Vogel, M.; Berg, T.; Danta, M.; Axel, B.; Mayr, C.; Bruno, R.; Tural, C.; Klausen, G.; Clotet, B.; Lutz, T.; Grunhage, F.; Rausch, M.; Nischalke, HD.; Schewe, K.; Bienek, B.; Haerter, G.; Sauerbruch, T.; Rockstroh, JK.; Spengler, U. 
    Effect of the interleukin-6 C174G gene polymorphism on treatment of acute and chronic hepatitis C in human immunodeficiency virus coinfected patients. 

    2007  Hepatology; 45 (4): 899-910. (IF: 10.446).       
    Franco, S.; Parera, M.; Aparicio, E.; Clotet, B.; Martinez, MA. 
    Genetic and catalytic efficiency structure of an HCV protease quasispecies. 

    2007  HIV Clin Trials; 8 (4): 213-220. (IF: 1.704)       
    Rachlis, A.; Clotet, B.; Baxter, J.; Murphy, R.; Lefebvre, E. 
    Safety, tolerability and efficacy of Darunavir (TMC114) with low-dose Ritonavir in treatment-experienced, hepatitis B or C co-infected patients in POWER 1 and 3. 

    2007  HIV Med; 8 (8): 568-570 (IF: 1.934).       
    Llibre, JM.; Perez-Alvarez, N. 
    Methodological accuracy in cross-trial comparisons of antiretroviral regimens in multitreated patients. 

    2007  HIV Med; 8: 259-264. (IF: 1.934).       
    Llibre, JM.; Perez-Alvarez, N.; Hill, A.; Moyle, G. 
    Relative antiviral efficacy of ritonavir-boosted darunavir and ritonavir-boosted tipranavir vs. control protease inhibitor in the POWER and RESIST trials. 

    2007  J Acquir Immune Defic Syndr.; 45 (4): 479-481. (IF: 3.946)       
    Clotet, B.; Negredo, E.; Girard, PM.; Youle, M.; Neubacher, D. 
    Compromised immunologic recovery in patients receiving tipranavir/ritonavir coadministered with tenofovir and didanosine in randomised: Evaluation of Strategic Intervention in multidrug-resistant patients with tipranavir (RESIST) studies. 

    2007  J Antimicrob Chemother (en prensa)       
    Negredo, E.; Puigdomènech, I.; Marfil, S.; Puig, J.; Pérez-Álvarez, N.; Ruiz, L.; Rey-Joly, C.; Clotet, B.; Blanco, J. 
    Association between HIV replication and cholesterol in peripheral blood mononuclear cells in HIV-infected patients interrupting HAART. 

    2007  J Antimicrob Chemother; 60 (2): 436-439. (IF: 3.891)       
    Moltó, J.; Santos, JR.; Negredo, E.; Miranda, C.; Videla, S.; Clotet, B. 
    Lopinavir/ritonavir monotherapy as a simplification strategy in routine clinical practice. 

    2007  J Hepatol; 47 (4): 447-450. (IF: 10.446).       
    Degos, F.; Tural, C. 
    Hepatocellular carcinoma in human immunodeficiency virus (HIV)-infected patients: is it really different, and if so, why? 

    2007  J Infect Dis.; 196 (2): 178-180. (IF: 5.363)       
    Clotet, B. 
    CCR5 inhibitors: promising yet challenging. 

    2007  J Leukoc Biol.; 82 (1): 72-78. (IF: 4.572)       
    De Arquer, GR.; Pena, R.; Cabrera, C.; Coma, G.; Ruiz-Hernández, R.; Guerola, R.; Clotet, B.; Ruiz, L.; Esté, JA.; Calle, LM.; Bofill, M. 
    Skewed expression and up-regulation of the IL-12 and IL-18 receptors in resting and activated CD4 T cells from HIV-1 infected patients. 

    2007  J Mass Spectrom.       
    Pruvost, A.; Théodoro, F.; Agrofolio, K.; Negredo, E.; Bénech. H. 
    Specificity enhancement with LC-positive ESI-MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate and tenofovir diphosphate in human peripheral blood mononuclear cells. 

    2007  J Viral Hepat; 14 (10): 704-713. (IF: 3.29)       
    Tural, C.; Solà, R.; Rubio, R.; Santín, M.; Planas, R.; Quereda, C.; Berenguer, J.; Montes-Ramirez, M.; Clotet, B.; and the CORAL-1 study group. 
    Safety and efficacy of an induction dose of pegylated interferon alpha-2a on early hepatitis C virus kinetics in HIV/HCV co-infected patients: the CORAL-1 multicentre pilot study. 

    2007  J Virol Methods (IF: 2.097).       
    Paredes, R.; Marconi, VC.; Campbell, TB.; Kuritzkes, DR. 
    Systematic evaluation of allele-specific real-time PCR for the detection of minor HIV-1 variants with pol and env resistance mutations. 

    2007  J Virol. (IF: 5.341)       
    Villena, C.; Prado, JG.; Puertas, MC.; Martinez, MA.; Clotet, B.; Ruiz, L.; Parkin, MT.; Menendez-Arias, L.; Martinez-Picado, J. 
    Relative fitness and replication capacity of a multinucleoside analogue-resistant clinical HIV-1 isolate with a deletion of codon 69 in the reverse transcriptase. 

    2007  J Virol. (IF: 5.341).       
    Gimenez-Barcons, M.; Clotet, B.; Martinez, MA. 
    Endoribonuclease-prepared siRNAs induce effective and specific inhibition of HIV-1 replication. 

    2007  J Virol; 81 (14): 7559-7570. (IF: 5.341).       
    Izquierdo-Useros, N.; Blanco, J.; Erkizia, I.; Fernadez-Figueras, MT.; Borras, FE.; Naranjo-Gomez, M.; Bofill, M.; Ruiz, L.; Clotet, B.; Martinez-Picado, J. 
    Maturation of blood-derived dendritic cells enhaces human immunodeficiency virus type 1 capture and transmission. 

    2007  J Virol; 81 (5): 2485-2496. (IF: 5.341).       
    Fernandez, G.; Clotet, B.; Martinez, MA. 
    Fidness landscape of human immunodeficiency virus type 1 protease quasispecies. 

    2007  JAIDS; 44: 139-147       
    Podzamczer, D.; Ferrer, E.; Sanchez, P.; Gatell, JM.; Crespo, M.; Fisac, C.; Lonca, M.; Sanz, J.; Niubo, J.; Veloso, S.; Llibre, JM.; Barrufet, P.; Ribas, MA.; Merino, E.; Ribera, E.; Martínez-Lacasa, J.; Alonso, C.; Aranda, M.; Pulido, F.; Berenguer, J.; Delegido, A.; Pedreira, J.; Lérida, A.; Rubio, R.; Del Río, L. for the ABCDE Study Team. 
    Less lipoatrophy and better lipid profile with abacavir as compared to stavudine. 96-week results of a randomized study. 

    2007  Journal of Acquired Immune Deficiency Syndrome; 46: 253-255.       
    Ferrer, E.; Niubo, J.; Crespo, M.; Gatell, JM.; Sanz, J.; Veloso, S.; Llibre, JM.; Barrufet, P.; Sanchez, P.; Podzamczer, D. for the ABCDE Study Team. 
    Genotypic resistance in HIV-infected naïve patients receiving abacavir plus lamivudine and efavirenz. 

    2007  Journal of the International Neuropsychological Society; 13 (1): Supplement S1: 19       
    Muñoz-Moreno, JA.; Fumaz, CR.; Ferrer, MJ.; Ávila, R.; Prats, A.; Guillamon, N.; Negredo, E.; Garolera, M.; Clotet, B.  
    Benefits of a cognitive rehabilitation program on Neurocognitive Impairment in HIV-infected patients. Preliminary Findings. 

    2007  Lancet; 369 (9568): 1169-1178. (IF: 25.800).       
    Clotet, B.; Bellos, N.; Molina, JM.; Cooper, D.; Goffard, JC.; Lazzarin, A.; Wohrmann, A.; Katlama, C.; Wilkin, T.; Haubrich, R.; Cohen, C.; Farthing, C.; Jayaweera, D.; Markowitz, M.; Ruane, P.; Spinosa-Guzman, S.; Lefebvre, E. 
    Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials. 

    2007  Lancet; 370 (9581): 39-48. (IF: 25.800).       
    Lazzarin, A.; Campbell, T.; Clotet, B.; Johnson, M.; Katlama, C.; Moll, A.; Towner, W.; Trottier, B.; Peeters, M.; Vingerhoets, J.; de Smedt, G.; Baeten, B.; Beets, G.; Sinha, R.; Woodfall, B. 
    Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1 infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial. 

    2007  Leuk Lymphoma; 48: 2058-2059       
    Xicoy, B.; Ribera, JM.; Romeu, J.; Mate, JL.; Millà, F.; Feliu, E. 
    Response to highly active antiretroviral therapy as the only therapy in an HIV-infected patient with interfollicular Hodgkin's lymphoma. 

    2007  Med Clin; 129 (2): 70-76       
    Negredo, E.; Pagés, M.; Ramírez, J. 
    A 50-year-old male with AIDS and retroperitoneal mass. 

    2007  Med Clin; 129 (8): 309-313       
    Bruguera, M.; Torres, M.; Campins, M.; Bayas, JM.; Segura, A.; Barrio, JL.; Esteban, R.; Gatell, JM.; Martínez, M.; Monés, J.; Plans, A.; Planas, R.; Serra, C.; Tural, C.; Villalbí, JR. 
    Risk of transmition of HIV or hepatitis B or C viruses from an infected physician. Preventive measures. 

    2007  Mol Biol Evol; 24 (2): 382-327. (IF: 6.726)       
    Parera, M.; Fernandez, G.; Clotet, B.; Martinez, MA. 
    HIV-1 protease catalytic efficiency effects caused by random single amino acid substitutions. 

    2007  Nutr Hosp; 22 (2): 229-243.       
    Polo, R.; Gómez-Candela, C.; Miralles, C.; Locutura, J.; Álvarez, J.; Barreiro, F.; Bellido, D.; Câncer, E.; Cànoves, D.; Domingo, P.; Estrada, V.; Fumaz, CR.; Galindo, MJ.; García-Benayas, T.; Iglesias, C.; Irles, JA.; Jimenez-Nacher, I.; Lozano, F.; Marqués, I.; Martinez-Alvarez, JR.; Mellado, MJ.; Miján, A.; Ramos, JT.; Riobo, P.; SPNS/GEAM/SENBA/SENPE/AEDN/SEDCA/GESIDA. 
    Recommendations from SPNS/GEAM/SENBA/SENPE/AEDN/SEDCA/GESIDA on nutrition in the HIV-infected patient. 

    2007  Pharmacoeconomics-Spanish Research articles; 4 (1): 25-36       
    Moreno, S.; Casado, MA.; Domingo, P.; Llibre, JM.; Martínez, E.; Miralles, C.; Santos, J.; Pérez-Elías, MJ.; Herrera, S.; Sánchez de la Rosa, R. 
    Análisis de minimización de costes de diferentes combinaciones de inhibidores de la transcriptasa inversa análogos de nucleósidos asociados a acontecimientos adversos en pacientes infectados por el VIH-1. 

    2007  Sex Trans Dis; 34 (3): 141-144.       
    Libois, A.; de Wit, S.; Poll, B.; Garcia, F.; Florence, E.; Del Río, A.; Sanchez, P.; Negredo, E.; Vandenbruaene, M.; Gatell, JM.; Clumeck, N. 
    HIV and syphili: when to perform a lumbar puncture. 

    2007  Ther Drug Mon: 29 (5): 648-651       
    Moltó, J.; Santos, JR.; Valle, M.; Miranda, C.; Miranda, J.; Blanco, A.; Negredo, E.; Clotet, B. 
    Monitoring atazanavir concentrations with boosted or unboosted regimens in HIV-infected patients in routine clinical practice. 

    2007  Top HIV Med; 15 (4): 119-125.       
    Johnson, VA.; Brun-Bezinet, F.; Clotet, B.; Gunthard, HF.; Kuritzkes, DR.; Pillay, D.; Schapiro, JM.; Richman, DD. 
    Update of the Drug Resistance Mutations in HIV-1: 2007. 

    2007  Virus Res; 123 (2): 161-169. (IF: 2.783).       
    Franco, S.; Tural, C.; Clotet. B.; Martinez, MA. 
    Complete nucleotide sequence of genotype 4 hepatitis C viruses isolated from patients coinfected with human immunodeficiency virus Type 1. 

    2006  AIDS Res Hum Retroviruses , 22 (1): 33-39       
    S Lopez , E Negredo , G Garrabou , J Puig , L Ruiz , E Sanjurjo , X Ramos , AB Infante , J Casademont , F Cardellach, B Clotet , O Miro. 
    Longitudinal study on mitochondrial effects of didanosine-tenofovir combination 

    2006  AIDS Res Hum Retroviruses , 22 (5) : 393-400       
    R Sola , J A Galeras , S Montoliu , C Tural , L Force , S Torra , S Montull , E R Castro , S Coll , D Fuster , P Barrufet , G Sirera , M D Gimenez , B Clotet , R Planas 
    Poor response to hepatitis C virus (HCV) therapy in HIV- and HCV-coinfected patients is not due to lower adherence to treatment. 

    2006  AIDS Res Hum Retroviruses, 22 (4): 321-329       
    A Bonjoch , R Paredes , P Domingo , M Cervantes , E Pedrol , E Ribera , L Force , J M Llibre , J Vilaro , D Dalmau , J Cucurull , J Mascaro , A Masabeu , N Perez-Alvarez , J Puig , D Cinguegrana , B Clotet 
    Long-term safety and efficacy of nevirapine-based approaches in HIV type 1-infected patients. 

    2006  AIDS Researh Human Retrovirus , 22 (9): 893-896       
    M Bofill , J Martinez-Picado , R Ruiz , C Cabrera , S Marfil , I Erkizia , R Bellido , J Romeu , B Clotet , L Ruiz 
    Naive CD4(+) T cells and recent thymic emigrant levels in treated individuals with HIV: clinical relevance. 

    2006  AIDS, 20 (14) : 1896-1898       
    A Bonjoch , E Negredo , J Puig , I Erkizia , T Puig , C Cabrera , L Ruiz , B Clotet 
    Viral failure in HIV-infected patients with long-lasting viral suppression who discontinued enfuvirtide. 

    2006  AIDS, 20 (16) : 2075-2080       
    C Cabrera, S Marfil , E Garcia , J Martinez-Picado , A Bonjoch , M Bofill , S Moreno , E Ribera , P Domingo , B Clotet , L Ruiz 
    Genetic evolution of gp41 reveals a highly exclusive relationship between codons 36, 38 and 43 in gp41 under long-term enfuvirtide-containing salvage regimen 

    2006  AIDS, 20 (8) : 1201-1204       
    G Sirera , S Videla , M Pinol , M P Canadas , M Llatjos , A L Ballesteros , F Garcia-Cuyas , E Castella , R Guerola , C Tural , C Rey-Joly , B Clotet 
    High prevalence of human papillomavirus infection in the anus, penis and mouth in HIV-positive men. 

    2006  AIDS. 20:619-21.       
    Negredo E, Clotet B, Puig J, Perez-Alvarez N, Ruiz L, Romeu J, Molto J, Rey-Joly C, Blanco J. 
    The effect of atorvastatin treatment on HIV-1-infected patients interrupting antiretroviral therapy. 

    2006  Antimicrob Agents Chemother 49 (10) : 4296-4304       
    B Bosch , J Blanco , E Pauls , I Clotet-Codina , M Armand-Ugon , B Grigorov , D Muriaux , B Clotet , J L Darlix , J A Este  
    Inhibition of coreceptor-independent cell-to-cell human immunodeficiency virus type 1 transmission by a CD4-immunoglobulin G2 fusion protein  

    2006  Antiviral Res. 69:173-80.       
    Bosch B, Clotet-Codina I, Blanco J, Pauls E, Coma G, Cedeno S, Mitjans F, Llano A, Bofill M, Clotet B, Piulats J, Este JA. 
    Inhibition of human immunodeficiency virus type 1 infection in macrophages by an alpha-v integrin blocking antibody. 

    2006  Antiviral Ther , 11 (4) : 473-482       
    D Fuster , R Planas , J Gonzalez , L Force , M Cervantes , J Vilaro , M Roget , I Garcia , E Pedrol , J Tor , AL Ballesteros , A Salas , G Sirera , S Videla , B Clotet , C Tural.  
    Results of a study of prolonging treatment with pegylated interferon-alpha2a plus ribavirin in HIV/HCV-coinfected patients with no early virological response. 

    2006  Antiviral Therapy, 11: 47–51       
    J Moltó, L Ruiz, M Valle, J Martinez-Picado, A Bonjoch, I Bravo, E Negredo, G M Heilek-Sneider, B Clotet 
    Increased antiretroviral potency by the addition of enfuvirtide to a four-drug regimen in antiretroviralnaive, HIV-infected patients 

    2006  Bioorg Med Chem 14:6255-82       
    Lysek R, Schutz C, Favre S, O'Sullivan AC, Pillonel C, Krulle T, Jung PM, Clotet-Codina I, Este JA, Vogel P.  
    Search for alpha-glucosidase inhibitors: new N-substituted valienamine and conduramine F-1 derivatives. 

    2006  Bioorg Med Chem Lett. 16:3541-4       
    Mugnaini C, Manetti F, Este JA, Clotet-Codina I, Maga G, Cancio R, Botta M, Corelli F. 
    Synthesis and biological investigation of S-aryl-S-DABO derivatives as HIV-1 inhibitors. 

    2006  Br J Clin Pharmacol , 62 (5) : 560-566       
    J Molto, A Blanco , C Miranda , J Miranda , J Puig , M Valle , M Delavarga , CR Fumaz , M J Barbanoj , B Clotet . 
    Variability in non-nucleoside reverse transcriptase and protease inhibitor concentrations among HIV-infected adults in routine clinical practice. 

    2006  Clinical and Experimental Immunology 145:535–544       
    Coma G, Peña R, Blanco J, Rosell A, Borras FE, Esté JA, ClotetB, Ruiz L, Parkhouse RME and Bofill M 
    Treatment of monocytes with interleukin (IL)-12 plus IL-18 stimulates survival, differentiation and the production of CXC chemokine ligands (CXCL)8, CXCL9 and CXCL10 

    2006  Enferm Infecc Microbiol Clin , 24 (4): 219-221       
    C Cabrera , B Clotet 
    Resistance genotyping in patients with therapeutic failure 

    2006  HIV Clin Trials 7:86-96       
    Youle M, Staszweski S, Clotet B, Arribas JR, Blaxhult A, Carosi G, Dejesus E, Di Perri G, Estrada V, Fisher M, Kovacs C, Kulasegaram R, Lazzarin A, Marriott D, Munoz L, Reynes J, Shalit P, Slim J, Tsoukas C, Vaccaro A, Vera J.  
    Concomitant use of an active boosted protease inhibitor with enfuvirtide in treatment-experienced, HIV-infected individuals: recent data and consensus recommendations. 

    2006  HIV Med , 7 (2): 67-74       
    A Hill , S Walmsley , B Clotet , J Molto 
    Analysis of genotypic and phenotypic clinical cut-off levels for ritonavir-boosted saquinavir. 

    2006  J Antimicrob Chemother , 58 (2) : 235-242       
    E Negredo , A Bonjoch , B Clotet 
    Benefits and concerns of simplification strategies in HIV-infected patients 

    2006  J Antimicrob Chemother 58:235-42       
    Negredo E, Bonjoch A, Clotet B.  
    Benefits and concerns of simplification strategies in HIV-infected patients. 

    2006  J Chem Inf Model 46:1344-51       
    Manetti F, Tintori C, Armand-Ugon M, Clotet-Codina I, Massa S, Ragno R, Este JA, Botta M.  
    A combination of molecular dynamics and docking calculations to explore the binding mode of ADS-J1, a polyanionic compound endowed with anti-HIV-1 activity. 

    2006  J Gen Virol , 87 (Pt 5) : 1285-1294       
    G Fernandez , A Llano, M Esgleas , B Clotet , J A Este , MA Martinez 
    Purifying selection of CCR5-tropic human immunodeficiency virus type 1 variants in AIDS subjects that have developed syncytium-inducing, CXCR4-tropic viruses 

    2006  J Leukoc Biol , 80 (3) : 659-667       
    E Pauls , J Senserrich , B Clotet , J A Esté 
    Inhibition of HIV-1 replication by RNA interference of p53 expression 

    2006  J Virol. 80:3617-3623.       
    Martinez-Picado J, Prado JG, Fry EE, Pfafferott K, Leslie A, Chetty S, Thobakgale C, Honeyborne I, Crawford H, Matthews P, Pillay T, Rousseau C, Mullins JI, Brander C, Walker BD, Stuart DI, Kiepiela P, Goulder P. 
    Fitness Cost of Escape Mutations in p24 Gag in Association with Control of Human Immunodeficiency Virus Type 1. 

    2006  J. Exp. Med.. 203: 529-539.        
    Draenert R, Allen TM, Liu Y, Wrin T, Chappey C, Verrill CL, Sirera G, Eldridge RL, Lahaie MP, Ruiz L, Clotet B, Petropoulos CJ, Walker BD, Martinez-Picado J.  
    Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus. 

    2006  Journal of Infectious Diseases. 194: 38-91       
    Gumà M, Cabrera C, Erkizia I, Bofill M, Clotet B, Ruiz L and Lopez-Botet M 
    Human Cytomegalovirus Infection Is Associated with Increased Proportions of NK Cells That Express the CD94/NKG2C Receptor in Aviremic HIV-1–Positive Patients 

    2006  Mini Rev Med Chem 6:91-108       
    Pettersson S, Clotet-Codina I, Este JA, Borrell JI, Teixido J.  
    Recent advances in combinatorial chemistry applied to development of anti-HIV drugs. 

    2006  Top HIV Med 14:125-30       
    Johnson VA, Brun-Vezinet F, Clotet B, Kuritzkes DR, Pillay D, Schapiro JM, Richman DD.  
    Update of the drug resistance mutations in HIV-1: Fall 2006. 

    2006  Virus Res        
    S Franco , C Tural , B Clotet , M A Martinez 
    Complete nucleotide sequence of genotype 4 hepatitis C viruses isolated from patients co-infected with human immunodeficiency virus type 1. 

    2005  AIDS 19: 2117-2125.       
    Mocroft A, Soriano V, Rockstroh J, Reiss P, Kirk O, de Wit S, Gatell J, Clotet B, Phillips AN, Lundgren JD; EuroSIDA Study Group. 
    Is there evidence for an increase in the death rate from liver-related disease in patients with HIV? 

    2005  J Infect Dis , 192 (6) : 992-1002       
    J K Rockstroh , A Mocroft , V Soriano , C Tural , M H Losso , A Horban , O Kirk , A Phillips , B Ledergerber , J Lundgren , EuroSIDA Study Group 
    Influence of hepatitis C virus infection on HIV-1 disease progression and response to highly active antiretroviral therapy  

    2005  J Virol , 80 (2) : 571-577       
    R Sabariegos , M Jiménez-Barcons , N Tapia , B Clotet , M A Martínez 
    Sequence homology required by human immunodeficiency virus type 1 to escape from short interfering RNAs.  

    2005  AIDS 19: 343-345       
    Negredo E, Martinez-Lopez E, Paredes R, Rosales J, Perez-Alvarez N, Holgado S, Gel S, del Rio L, Tena X, Rey-Joly C, Clotet B. 
    Reversal of HIV-1-associated osteoporosis with once-weekly alendronate. 

    2005  AIDS 19: 569-575       
    Barrios A, Rendon A, Negredo E, Barreiro P, Garcia-Benayas T, Labarga P, Santos J, Domingo P, Sanchez-Conde M, Maida I, Martin-Carbonero L, Nunez M, Blanco F, Clotet B, Sambeat MA, Gil P, Gonzalez-Lahoz J, Cooper D, Soriano V. 
    Paradoxical CD4+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine. 

    2005  AIDS 19:1697-1700.        
    Moncunill G, Negredo E, Bosch L, Vilarrasa J, Witvrouw M, Llano A, Clotet B, Este JA 
    Evaluation of the anti-HIV activity of statins. 

    2005  AIDS, 19 : 2117-2125       
    A Mocroft , V Soriano , J Rockstroh , P Reiss , O Kirk , S de Wit , J Gatell , B Clotet , A N Philips , J D Lundgren , for the EuroSIDA study group 
    Evidence for an increase in the death rate from liver-related disease in patients with HIV : Teh EuroSIDA study 

    2005  Antimicrob Agents Chemother, 49 (5) : 1907-1914       
    A Pruvost , E Negredo , H Benech , F Theodoro , J Puig , E Grau , E García , J Moltó , J Gras , B clotet 
    Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients.  

    2005  Antimicrob Agents Chemother. 49:3926-3929       
    Blanco J, Clotet-Codina I, Bosch B, Armand-Ugon M, Clotet B, Este JA 
    Multiparametric assay to screen and dissect the mode of action of anti-human immunodeficiency virus envelope drugs. 

    2005  Antimicrob Agents Chemother. 49:4296-304.       
    Bosch B, Blanco J, Pauls E, Clotet-Codina I, Armand-Ugon M, Grigorov B, Muriaux D, Clotet B, Darlix JL, Este JA 
    Inhibition of coreceptor-independent cell-to-cell human immunodeficiency virus type 1 transmission by a CD4-immunoglobulin G2 fusion protein. 

    2005  Antimicrobial Agents and Chemotherapy 49(5):1907-14       
    Pruvost A, Negredo E, Benech H, Theodoro F, Puig J, Grau E, Garcia E, Molto J, Grassi J, Clotet J 
    Measurement of Intracellular Didanosine and Tenofovir Phosphorylated Metabolites and Possible Interaction of the Two Drugs in Human Immunodeficiency Virus-Infected Patients 

    2005  Antiviral Therapy 10: 825-832.       
    Barrios A, Negredo E, Domingo P, Estrada V, Labarga P, Asensi V, Morales D, Santos J, Clotet B, Soriano V; EFADITE Study Group. 
    Simplification therapy with once-daily didanosine, tenofovir and efavirenz in HIV-1-infected adults with viral suppression receiving a more complex antiretroviral regimen: final results of the EFADITE trial. 

    2005  Antiviral Therapy 10: 791-802.       
    Thymidine analogue mutation profiles: factors associated with acquiring specific profiles and their impact on the virological response to therapy. 
    Cozzi-Lepri A, Ruiz L, Loveday C, Phillips AN, Clotet B, Reiss P, Ledergerber B, Holkmann C, Staszewski S, Lundgren JD; EuroSIDA Study Group. 

    2005  Antiviral Therapy 10: 841-847       
    Fuster D, Huertas JA, Gomez G, Sola R, Gonzalez Garcia J, Vilaro J, Pedrol E, Force L, Tor J, Sirera G, Videla S, Planas R, Clotet B, Tural C; PEG-TOX Research Group.  
    Baseline factors associated with haematological toxicity that leads to a dosage reduction of pegylated interferon-alpha2a and ribavirin in HIV- and HCV-coinfected patients on HCV antiviral therapy. 

    2005  Clinical Infectious Diseases 40:1342–9       
    M Gimenez-Barcons, M Ribera, A Llano, B Clotet, JA Este, MA Martinez 
    Analysis of Chemokine and Cytokine Expression in Patients with HIV and GB Virus Type C Coinfection 

    2005  Clinical Infectious Diseases 41: 901-905       
    Negredo E, Bonjoch A, Paredes R, Puig J, Clotet B. 
    Compromised immunologic recovery in treatment-experienced patients with HIV infection receiving both tenofovir disoproxil fumarate and didanosine in the TORO studies.  

    2005  Clinical Infectious Diseases; 41:729–37       
    Prado JG, Parkin NT, Clotet B, Ruiz L, Martinez-Picado J 
    HIV Type 1 Fitness Evolution in Antiretroviral-Experienced Patients with Sustained CD4+ T Cell Counts but Persistent Virologic Failure 

    2005  Expert Opin Pharmacother. 6: 1565-1572.       
    Fuster D, Clotet B.  
    Review of atazanavir: a novel HIV protease inhibitor.  

    2005  HIV Med 6: 107-13       
    Johnson M, Nieto-Cisneros L, Horban A, Arasteh K, Gonzalez-Garcia J, Artigas J, Clotet B, Danise A, Landman R, Proll S, Snowden W, Foreman R, Smith P. 
    Comparison of gastrointestinal tolerability and patient preference for treatment with the 625 mg and 250 mg nelfinavir tablet formulations. 

    2005  Immunologia , 24 (2) : 246-260       
    A Llano , J A Esté 
    Cytokines, chemokines and their receptors as modulators of the replication and evolution of HIV-1 

    2005  Journal Antimicrob Chemother. 55: 824-827.       
    Ballesteros AL, Fuster D, Planas R, Clotet B, Tural C.  
    Role of viral kinetics under HCV therapy in HIV/HCV-coinfected patients 

    2005  Journal of Acquired Immune Deficiency Syndromes 38: 560-565       
    Fumaz CR, Munoz-Moreno JA, Molto J, Negredo E, Ferrer MJ, Sirera G, Perez-Alvarez N, Gomez G, Burger D, Clotet B. 
    Long-Term Neuropsychiatric Disorders on Efavirenz-Based Approaches: Quality of Life, Psychologic Issues, and Adherence. 

    2005  Journal of Acquired Immune Deficiency Syndromes 38: 47-52       
    Negredo E, Molto J, Burger D, Cote H, Miro O, Ribalta J, Martinez E, Puig J, Ruiz L, Salazar J, Lopez S, Montaner J, Rey-Joly C, Clotet B. 
    Lopinavir/ritonavir plus nevirapine as a nucleoside-sparing approach in antiretroviral-experienced patients (NEKA study). 

    2005  Journal of Acquired Immune Deficiency Syndromes 40: 413-421.       
    Trottier B, Walmsley S, Reynes J, Piliero P, O'Hearn M, Nelson M, Montaner J, Lazzarin A, Lalezari J, Katlama C, Henry K, Cooper D, Clotet B, Arasteh K, Delfraissy JF, Stellbrink HJ, Lange J, Kuritzkes D, Eron JJ Jr, Cohen C, Kinchelow T, Bertasso A, Labriola-Tompkins E, Shikhman A, Atkins B, Bourdeau L, Natale C, Hughes F, Chung J, Guimaraes D, Drobnes C, Bader-Weder S, Demasi R, Smiley L, Salgo MP. 
    Safety of enfuvirtide in combination with an optimized background of antiretrovirals in treatment-experienced HIV-1-infected adults over 48 weeks. 

    2005  Journal of Immunology, 174: 5655-5664       
    Colobran R., Adreani P, Ashhab Y., Llano A., Esté JA., Dominguez O., Pujol-Borrell R., Juan M. 
    Multiple products derived from two CCl4 loci: high incidence of a new polymorphism in HIV+ patients. 

    2005  Journal of Medicinal Chemistry 48: 8000-8008       
    Manetti F, Este JA, Clotet-Codina I, Armand-Ugon M, Maga G, Crespan E, Cancio R, Mugnaini C, Bernardini C, Togninelli A, Carmi C, Alongi M, Petricci E, Massa S, Corelli F, Botta M. 
    Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity. 

    2005  Journal of Acquired Immune Deficiency Syndromes 39: 313-316.       
    Bonjoch A, Paredes R, Galvez J, Miralles C, Videla S, Martinez E, Miranda J, Munoz-Moreno JA, De la Torre J, Prieto A, Vilades C, Clotet B; and the SimplifiHAART Study Group. 
    Antiretroviral treatment simplification with 3 NRTIs or 2 NRTIs plus nevirapine in HIV-1-infected patients treated with successful first-line HAART. 

    2005  Journal of Acquired Immune Deficiency Syndromes 40: 404-412        
    M Nelson, K Arasteh, B Clotet, DA Cooper, K Henry, C Katlama, JP Lalezary, A Lazzarin, J SG Montaner, M O’Hearn, PJ Piliero, J Reynes, B Trottier, S Walmsley, C Cohen, J Eron Jr, DS Kuritzkis, J Lange, HJ Stellbrink, JD Delfraissy.  
    Durable efficacy of enfuvirtide over 48 wks among demographic, baseline and treatment subgroups in the TORO 1 and TORO 2 clinical trials.  

    2005  Journal of Clinical Microbiology 43: 436–438       
    Martinez-Picado J, Morales-Lopetegi K, Villena C, Gutiérrez C, Izquierdo , Marfil S, Clotet B, Ruiz L 
    Evidence for Preferential Genotyping of a Minority Human Immunodeficiency Virus Population Due to Primer-Template Mismatching during PCR-Based Amplification 

    2005  Journal of Virology 79: 5907–13       
    J Martinez-Picado, T Wrin, SDW Frost, B Clotet, L Ruiz, AJ Leigh Brown, CJ Petropoulos, NT Parkin 
    Phenotypic Hypersusceptibility to Multiple Protease Inhibitors and Low Replicative Capacity in Patients Who Are Chronically Infected with Human Immunodeficiency Virus Type 1 

    2005  Med Clin , 124 (14) : 525-531       
    A Jaen , J Casabona , A Esteve , J M Miró , C Tural , E Ferrer , M Riera , F Segura , L Force , O Sued , J Vilaró , A Masabeu , I García , E Dorca , J Altés , G Navarro , D Podzamczer , C Villalonga , B Clotet , J M Gatell , Grupo de estudio Piscis 
    Características clinicopidemiológicas y tendencias en el tratamiento antiretroviral de un cohorte de pacientes con infección por el virus de la immunodeficiencia humana. 

    2005  Med Clin 124 (16) : 618 - 619       
    C Cabrera , B Clotet 
    Mutaciones de resistencia a agentes antiretrovirales en pacientes con infección por el VIH 

    2005  Med. Clin , 125 (4) : 127-131       
    G Sirera , S Videla , E Castella , L Cavallé , N Grané , M Llatjós , C Tural , E Negredo , A Fernández, C Rey-Joly , B Clotet 
    Contribución de la captura de híbridos de segunda generación del virus del papiloma humano en el cribado de afección cervical en mujeres con infección por el VIH 

    2005  Top HIV Med. 13: 51-57.       
    Johnson VA, Brun-Vezinet F, Clotet B, Conway B, Kuritzkes DR, Pillay D, Schapiro J, Telenti A, Richman D. 
    Update of the Drug Resistance Mutations in HIV-1: 2005.  

    2005  Topics in HIV Medicine 13:125-31       
    Johnson VA, Brun-Vezinet F, Clotet B, Conway B, Kuritzkes DR, Pillay D, Schapiro JM, Telenti A, Richman DD. 
    Update of the drug resistance mutations in HIV-1: Fall 2005. 

    2005  Virology 343: 141-149       
    Armand-Ugon M, Clotet-Codina I, Tintori C, Manetti F, Clotet B, Botta M, Este JA 
    The anti-HIV activity of ADS-J1 targets the HIV-1 gp120.  

    2005  Virology. 338:1-8       
    Tapia N, Fernandez G, Parera M, Gomez-Mariano G, Clotet B, Quinones-Mateu M, Domingo E, Martinez MA 
    Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection 

    2004  Top HIV Med 12( 4 ): 119-124.       
    V A Johnson , F Brun-Vezinet , B Clotet , B Conway , R T D'Aquila , L M Demeter , D R Kuritzkes , D Pillay , J M Schapiro , A Telenti , D E Richman  
    Update of the drug resistance mutations in HIV-1: 2004  

    2004  AIDS 18 (12) : 1673-1682       
    J Barretina , J Blanco , A Bonjoch , A Llano , B Clotet , J A Este 
    Immunological and virological study of enfuvirtide-treated HIV-positive patients 

    2004  AIDS 18: ..59–66       
    Ballesteros A L, Franco S, Fuster D, Planas R, Martínez M A, Acosta L, Sirera G, Salas A, Tor J, Rey-Joly C, Clotet B, Tural C. 
    Early HCV dynamics on Peg-interferon and ribavirin in HIV/HCV co-infection: indications for the investigation of new treatment approaches 

    2004  AIDS 18: .459-463       
    Negredo E, Molto J, Burger D, Viciana P, Ribera E, Paredes R, Juan M, Ruiz L, Puig J, Pruvost A, Grassi J, Masmitja E, Clotet B. 
    Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load. 

    2004  AIDS 18: .819-21       
    Negredo E, Ribalta J, Ferre R, Salazar J, Rey-Joly C, Sirera G, Masana L, Clotet B. 
    Efavirenz induces a striking and generalized increase of HDL-cholesterol in HIV-infected patients. 

    2004  AIDS 18: 1137-1146       
    Clinical management of treatment-experienced, HIV-infected patients with the fusion inhibitor enfuvirtide: consensus recommendations. 
    Clotet B, Raffi F, Cooper D, Delfraissy JF, Lazzarin A, Moyle G, Rockstroh J, Soriano V, Schapiro J. 

    2004  AIDS 18: 1673-1682       
    Barretina J, Blanco J, Bonjoch A, Llano A, Clotet B, Este JA 
    Immunological and virological study of enfuvirtide-treated HIV-positive patients 

    2004  Aids Ciber Journal 7 (6)        
    J A Muñoz , C R Fumaz , A Prats , M J Ferrer , B Clotet 
    Evaluación de los déficit cognitivos en pacientes infectados por el VIH 

    2004  AIDS Research and Human Retroviruses 20: 1293-1297       
    Fuster D, Planas R, Muga R, Ballesteros AL, Santos J, Tor J, Sirera G, Guardiola H, Salas A, Cabre E, Ojanguren I, Barluenga E, Rey-Joly C, Clotet B, Tural C. 
    Advanced liver fibrosis in HIV/HCV-coinfected patients on antiretroviral therapy. 

    2004  AIDS Research and Human Retroviruses 20: 1283–1288       
    J Moltó, L Ruiz, J Romeu, J Martinez-Picado, E Negredo,C Tural, G Sirera, B Clotet 
    Influence of Prior Structured Treatment Interruptions on the Length of Time without Antiretroviral Treatment in Chronically HIV-Infected Subjects 

    2004  AIDS Reviews 6: 123-30       
    Clotet B. 
    Strategies for overcoming resistance in HIV-1 infected patients receiving HAART. 

    2004  AIDS, 18 : 1-12       
    R Paredes , B Clotet 
    New antiretroviral drugs and approaches to HIV treatment 

    2004  Antimicrob Agents and Chemotherapy 48: 4256-4262       
    Ribera E, Lopez RM, Diaz M, Pou L, Ruiz L, Falco V, Crespo M, Azuaje C, Ruiz I, Ocana I, Clotet B, Pahissa A. 
    Steady-state pharmacokinetics of a double-boosting regimen of saquinavir soft gel plus lopinavir plus minidose ritonavir in human immunodeficiency virus-infected adults. 

    2004  Antimicrob Agents Chemother. 48 (11 ): 4256 - 4262       
    E Ribera , R M López , M Diaz , L Pou , L Ruiz , V Falcó , M Crespo , C Azuaje , L Ruiz , I Ocaña , B Clotet , A Pahissa 
    Steady-state pharmacokinetics of a double-boosting regimen of saquinavir soft gel plus lopinavir plus minidose ritonavir in human immunodeficiency virus-infected adults  

    2004  Antivir Ther 9: 787-800.        
    Cabrera C, Cozzi-Lepri A, Phillips AN, Loveday C, Kirk O, Ait-Khaled M, Reiss P, Kjaer J, Ledergerber B, Lundgren JD, Clotet B, Ruiz L; EuroSIDA Study Group. 
    Baseline resistance and virological outcome in patients with virological failure who start a regimen containing abacavir: EuroSIDA study. 

    2004  Antivir Ther 9: 969-77       
    Ballesteros AL, Miro O, Lopez S, Fuster D, Videla S, Martinez E, Garrabou G, Salas A, Cote H, Tor J, Rey-Joly C, Planas R, Clotet B, Tural C. 
    Mitochondrial effects of a 24-week course of pegylated-interferon plus ribavirin in asymptomatic HCV/HIV co-infected patients on long-term treatment with didanosine, stavudine or both. 

    2004  Antiviral Therapy 9: 335-342       
    Negredo E, Molto J, Munoz-Moreno JA, Pedrol E, Ribera E, Viciana P, Galindos MJ, Miralles C, Burger D, Rodriguez Fumaz C, Puig J, Gel S, Rodriguez E, Videla S, Ruiz L, Clotet B. 
    Safety and efficacy of once-daily didanosine, tenofovir and nevirapine as a simplification antiretroviral approach. 

    2004  Antiviral Therapy 9: 465-478       
    Brun-Vezinet F, Costagliola D, Khaled MA, Calvez V, Clavel F, Clotet B, Haubrich R, Kempf D, King M, Kuritzkes D, Lanier R, Miller M, Miller V, Phillips A, Pillay D, Schapiro J, Scott J, Shafer R, Zazzi M, Zolopa A, DeGruttola V. 
    Clinically validated genotype analysis: guiding principles and statistical concerns. 

    2004  Antiviral Therapy 9:889–893       
    E Negredo, R Paredes, J Peraire, E Pedrol, H Côté, S Gel, CR Fumaz, L Ruiz, V Abril, E Rodriguez de Castro, C Ochoa, J Martinez-Picado, J Montaner, C Rey-Joly, B Clotet on behalf of the Swatch Study Team 
    Alternation of antiretroviral drug regimens for HIV infection. Efficacy, safety and tolerability at week 96 of the Swatch Study 

    2004  Business Briefing : long term healthcare : 2-8       
    E Negredo , L Ruiz , R Paredes , D Fuster , J Molto , B Clotet 
    Management of antiretroviral drug resistance in HIV-1 infected patients 

    2004  Clin. Exp. Immunol. 138: 460-465       
    M Bofill, E Almirall, A McQuaid, R Peña, R Ruiz-Hernandez, M Naranjo, L Ruiz, B Clotet & FE Borras 
    Differential expression of the cytokine receptors for human interleukin (IL)-12 and IL-18 on lymphocytes of both CD45RA+ and CD45RO+ phenotype from tonsils, cord and adult peripheral blood 

    2004  Curr Pharm Des , 10 (15) : 1845-1860       
    L Menéndez-Arias, J A Esté 
    HIV-resistance to viral entry inhibitors 

    2004  Drug Discovery Today Technologies, 1 : 135-140       
    E Pauls , M A Martínez , B Clotet , J A Esté 
    RNA interference of HIV coreceptors 

    2004  Enferm Infecc Microbiol Clin 22: 564-642       
    Iribarren JA, Labarga P, Rubio R, Berenguer J, Miro JM, Antela A, Gonzalez J, Moreno S, Arrizabalaga J, Chamorro L, Clotet B, Gatell JM, Lopez-Aldeguer J, Martinez E, Polo R, Tuset M, Viciana P, Santamaria JM, Kindelan JM, Ribera E, Segura F; Grupo de Estudio de Sida; Consejo Asesor Clinico del Plan Nacional sobre el Sida del Ministerio de Sanidad y Consumo. 
    [Spanish GESIDA/Nacional AIDS Plan Recommendations for antiretroviral therapy in HIV-infected Adults (October 2004)] 

    2004  GM Entorno Hospitalario. Diciembre :10       
    A Bonjoch , E Negredo , B Clotet 
    Indicaciones actuales y perspectivas futuras para los pacientes VIH1+ 

    2004  HIV Clin Trials 5: 33-9       
    Clotet B, Carmena J, Pulido F, Luque I, Rodriguez-Alcantara F; COL30494 Cohort Study Members. 
    Adherence, quality of life, and general satisfaction with co-formulated zidovudine, lamivudine, and abacavir on antiretroviral-experienced patients. 

    2004  Immunology. International Proceedings. Medimon : 25-28       
    M Bofill , R Peña , R Ruiz-Hernandez , M Naranjo , B Clotet , F E Borras 
    The Cytokine receptors for human IL-12 and IL-18 are preferentially expressed on effector memory lymphocytes 

    2004  J Acquir Immune Defic Syndr 38 (1) : 47-52       
    E Negredo , J Moltó , D Burger , H Cote , J Ribalta , O Miró , L Ruiz , J Puig , J Salazar , S Loopez , P Domingo , S Videla , B Clotet 
    Lopinavir/ritonavir plus nevirapine as a nucleoside-sparing approach in antiretroviral-experienced patients (NEKA study).  

    2004  J HIV Ther 9: 75-8.       
    Molto J, Clotet B. 
    Therapeutic drug monitoring of antiretroviral agents scenario. 

    2004  J Viral Hepat. 11: 2-17       
    Soriano V, Miro JM, Garcia-Samaniego J, Torre-Cisneros J, Nunez M, del Romero J, Martin-Carbonero L, Castilla J, Iribarren JA, Quereda C, Santin M, Gonzalez J, Arribas JR, Santos I, Hernandez-Quero J, Ortega E, Asensi V, del Pozo MA, Berenguer J, Tural C, Clotet B, Leal M, Mallolas J, Sanchez-Tapias JM, Moreno S, Gatell JM, Tellez MJ, Rubio R, Ledesma E, Domingo P, Barreiro P, Pedreira J, Romero M, Gonzalez-Lahoz J, Lissen E. 
    Consensus conference on chronic viral hepatitis and HIV infection: updated Spanish recommendations. 

    2004  J. Clin. Microbiol. 42 (4): 1620-1625       
    J.G. Prado, A. Shintani, M. Bofill, B. Clotet, L. Ruiz, and J. Martinez-Picado 
    Lack of Longitudinal Intrapatient Correlation between p24 Antigenemia and Levels of Human Immunodeficiency Virus (HIV) Type 1 RNA in Patients with Chronic HIV Infection during Structured Treatment Interruptions 

    2004  Journal of Biological Chemistry 279: 24569-24577       
    Matamoros T, Franco S, Vázquez-Álvarez BM, Mas A, Martínez MA, Menéndez-Arias L. 
    Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain (Effect of mutations D67N and T215Y on removal of thimidine nucleotide analogues from blocked CKED DNA primers)  

    2004  Journal of Infectious Diseases 189: 1444-51       
    Parera M, Ibanez A, Clotet B, Martinez MA. 
    Lack of evidence for protease evolution in HIV-1-infected patients after 2 years of successful highly active antiretroviral therapy. 

    2004  Journal of Infectious Diseases; 189:1444–51       
    Parera, M., Ibáñez, A., Clotet, B., and Martinez, M. A. 
    Lack of Evidence for Protease Evolution in HIV-1–Infected Patients after 2 Years of Successful Highly Active Antiretroviral Therapy 

    2004  Journal of Leukocyte Biology 76:804-811       
    Blanco J, Barretina J, Clotet B, Esté JA. 
    R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism. 

    2004  Journal of Virology vol.78: 14057–14061       
    M Parera, B Clotet, and MA Martinez 
    Genetic Screen for Monitoring Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease 

    2004  Med Clin , 123 (12) : 460-462       
    C Tural , B Clotet 
    La era del tratamiento antiretroviral de gran actividad y de la coinfección por el VHC 

    2004  Med Clin 122: 696-697       
    Paredes R, Clotet B. 
    [Duration of antiretroviral combinations] 

    2004  Med Clin 123: 460-462       
    Tural C, Clotet B. 
    [The era of antiretroviral therapy... and the era of hepatitis C virus coinfection] 

    2004  N Engl J Med. 2004 350: 1053-4; author reply 1053-4       
    Clotet B. 
    Comparison of regimens as initial therapy for HIV. 

    2004  Top HIV Med 12: 119-24       
    Johnson VA, Brun-Vezinet F, Clotet B, Conway B, D'Aquila RT, Demeter LM, Kuritzkes DR, Pillay D, Schapiro JM, Telenti A, Richman DD. 
    Update of the drug resistance mutations in HIV-1: 2004. 

    2004  Vaccine 22: 2966-73       
    Fernandez-Cruz E, Moreno S, Navarro J, Clotet B, Bouza E, Carbone J, Pena JM, Perez Molina J, Podzamczer D, Rubio R, Ocana I, Pulido F, Viciana P, Maradona JA, Blazquez R, Barros C, Quereda C, Rodriguez-Sainz C, Gil J, Abad ML, Diaz L, Canto C, Munoz MA, Ferrer E, Jou A, Sirera G, Diaz M, Lopez F, Gatell JM, Gonzalez-Lahoz J; STIR-2102 TEAM. 
    Therapeutic immunization with an inactivated HIV-1 Immunogen plus antiretrovirals versus antiretroviral therapy alone in asymptomatic HIV-infected subjects. 

    2004  Virology 325 (2) : 389-398       
    M DBobardt , M Armand-Ugon , Clotet I, Zhang , David G, Este JA, Gallay PA.  
    Effect of polyanion-resistance on HIV-1 infection.  

    2004  Virology 326: 103-112       
    Prado JG, Franco S, Matamoros T, Ruiz L, Clotet B, Menéndez-Arias L, Martínez MA, Martinez-Picado J 
    Relative replication fitness of multi-nucleoside analogue-resistant HIV-1 strains bearing a dipeptide insertion in the fingers subdomain of the reverse transcriptase and mutations at codons 67 and 215 

    2003  AIDS 17 Suppl 4: S85-96       
    Paredes R, Clotet B. 
    New antiretroviral drugs and approaches to HIV treatment. 

    2003  AIDS 17:1741-51       
    A Mocroft, L Ruiz, P Reiss, B Ledergerber, C Katlama, A Lazzarin, F-D Goebel, AN Phillips, B Clotet, JD Lundgren, for the EuroSIDA study group 
    Virological rebound after suppression on highly active antiretroviral therapy 

    2003  AIDS Cyber J , 6 : 2       
    D Fuster , A Ballesteros , G Sirera , A Salas , C Tural , B Clotet 
    Factores pronósticos de la hepatitis crónica VHC+ en pacientes VIH+ 

    2003  AIDS Cyber J 6 (4) : 1-24       
    J M Gatell , B Clotet , D Podzamczer , J M Miró , J Mallolas , C Fortuny 
    Tratamiento antiretroviral en el año 2003 para adultos , adolescentes y niños 

    2003  AIDS Reviews 5: 19-24       
    Clotet B, Negredo E.  
    HIV protease inhibitors and dyslipidemia. 

    2003  Ann Hematol 82:500-505       
    Barretina, J., Junca, J., Llano, A., Gutierrez, A. Flores, A., Blanco, J., Clotet, B., Este, J. A. 
    CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease 

    2003  Ann Intern Med 139 (2) : 81-89.       
    L Ruiz , E Ribera , A Bonjoch , J Romeu , J Martinez-Picado , R Paredes , M Díaz , S Marfil , E Negredo , J García-Prado , C Tural , G Sirera , B Clotet 
    Role of a therapy interruption prior to 5-drug antiretroviral salvage regimen. The Retrogene Study 

    2003  Ann Intern Med 139:81-9.       
    J Martinez-Picado, E Negredo, L Ruiz, A Shintani, CR Fumaz, C Zala, P Domingo, J Vilaro, JM Llibre, P Viciana, K Hertogs, C Boucher, RT D’Aquila, B Clotet, and the SWATCH Study Team 
    Alternation of Antiretroviral Drug Regimens for HIV Infection: A Randomized, Controlled Trial 

    2003  Ann Intern Med. 15; 139(2) : 81-89.        
    J Martinez-Picado , E Negredo , L Ruiz , C R Fumaz , A Shintani , C Zala , P Domingo , J Vilaró , J M Llibre , P Viciana , K Hertogs, Ch Boucher , R D'Aquila , B Clotet , SWATCH study team 
    Alternation of antiretroviral drug regimens for HIV infection. A randomized, controlled trial 

    2003  Antimicrob Agents Chemother 47: 1760-5       
    Martinez, MA, and Clotet, B. 
    Genetic Screen for Monitoring Hepatitis C Virus NS3 Serine Protease Activity 

    2003  Antiv Res 59: 137-42       
    M Armand-Ugón, A Gutiérrez, B Clotet, JA Esté 
    HIV-1 resistance to the gp41-dependent fusion inhibitor C-34 

    2003  Antivir Ther 8: 1-8       
    Armand-Ugon M, Quinones-Mateu ME, Gutierez A, Barretina J, Blanco J, Schols D, De Clercq E, Clotet B, Este JA. 
    Reduced fitness of HIV-1 resistant to CXCR4 antagonists. 

    2003  Antivir Ther 8: 127-136       
    Cozzi-Lepri A, Phillips AN, Miller V, Katlama C, Ledergerber B, Vella S, Weber J, Bruun JN, Kirk O, Clotet B, Lundgrens JD. 
    Changes in viral load in people with virological failure who remain on the same HAART regimen. 

    2003  Antiviral Res 59 (2) : 137 - 142       
    M Armand-Ugon, A Gutierrez , B Clotet , J A Esté 
    HIV-1 resistance to the gp41-dependent fusion inhibitor C-34.  

    2003  Antiviral Ther , 8, 1 : 1-8       
    M Armand-Ugon , M E Quiñones-Mateu , A Gutierrez , J Blanco , D Sxhols , E De Clercq , B Clotet , J A Esté 
    Lower fitness of human immunodeficiency virus type 1 resistant to CXCR4 antagonists 

    2003  Antiviral Ther 8 : 91-100       
    A Cozzi-Lepri , A N Philips , V Miller , C Katlama , B Ledergerber , S Vella , J Weber , J N Bruun , O Kirk , B Clotet , J D Lundgren 
    Changes in viral load in people with virological failure who remain on the same HAART regimen 

    2003  Antiviral Ther 8:155-161       
    Barretina J, Blanco J, Armand-Ugon M, Gutierrez A, Clotet B, Este JA. 
    Anti-HIV-1 activity of enfuvirtide (T-20) by inhibition of bystander cell death. 

    2003  Arch Intern Med 163: 1220-1226       
    Fagard, C., Oxenius, A., Gunthard, H., Garcia, F., Le Braz, M., Mestre, G., Battegay, M., Furrer, H., Vernazza, P., Bernasconi, E., Telenti, A., Weber, R., Leduc, D., Yerly, S., Price, D., Dawson, S. J., Klimkait, T., Perneger, T. V., McLean, A., Clotet, B., Gatell, J. M., Perrin, L., Plana, M., Phillips, R., Hirschel, B. 
    A prospective trial of structured treatment interruptions in human immunodeficiency virus infection 

    2003  Clin Infect Dis 37(1) :113-128       
    M S Hirsch , F Brun-Vezinet , B Clotet , B Conway , D R Kuritzkes , R T D'Aquila , L M Demeter , S M Hammer , V A Johnson , C Loveday , J W Mellors , D MJacobsen , D D Richman  
    Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel 

    2003  Clin Infect Dis 37:113-28       
    MS Hirsch, F Brun-Vezinet, B Clotet, B Conway, DR Kuritzkes, RT D’Aquila, LM Demeter, SM Hammer, VA Johnson, C Loveday, JW Mellors, DM Jacobsen, DD Richman 
    Antiretroviral Drug Resistance Testing in Adults Infected with Human Immunodeficiency Virus Type 1: 2003 Recommendations of an International AIDS Society–USA Panel 

    2003  Clin Invest Arterioscl , 15 : 1 , 29-34       
    B Clotet , L Masana , J Pedro-Botet 
    Guía del manejo de las dislipemias en los pacientes infectados por el VIH: recomendaciones farmacológicas 

    2003  IAPAC Mon. 9: 145-165       
    Fumaz CR, Clotet B. 
    Assessment of changes in adherence and quality of life after the simplification of antiretroviral treatment. 

    2003  J Acquir Immune Defic Syndr 34 Suppl 1: S79-84       
    Clotet B, van der Valk M, Negredo E, Reiss P. 
    Impact of nevirapine on lipid metabolism. 

    2003  J Antimicrob Chemother 52: 464-8       
    Laguna, F., Videla, S., Jimenez-Mejias, M. E., Sirera, G., Torre-Cisneros, J., Ribera, E., Prados, D., Clotet, B., Sust, M., Lopez-Velez, R., Alvar, J., The Spanish, H. I. V. Leishmania Study Group 
    Amphotericin B lipid complex versus meglumine antimoniate in the treatment of visceral leishmaniasis in patients infected with HIV: a randomized pilot study 

    2003  J Gen Virol 84: 2217-28       
    J Weber, HR Rangel, B Chakraborty, M Tadele, MA Martinez, J Martinez-Picado, ML Marotta, M Mirza, L Ruiz, B Clotet, T Wrin, CJ Petropoulos, ME Quiñones-Mateu 
    A novel TaqMan real-time PCR assay to estimate ex vivo human immunodeficiency virus type 1 fitness in the era of multi-target (pol and env)antiretroviral therapy 

    2003  J Gen Virol 84: 607-13       
    Tapia N, Franco S, Puig-Basagoiti F, Menendez C, Alonso PL, Mshinda H, Clotet B, Saiz JC, Martinez MA.  
    Influence of human immunodeficiency virus type 1 subtype on mother-to-child transmission.  

    2003  J Infect Dis 188: 1827-33       
    Walmsley S, Henry K, Katlama C, Nelson M, Castagna A, Reynes J, Clotet B, Hui J, Salgo M, DeMasi R, Delehanty J. 
    Enfuvirtide (T-20) cross-reactive glycoprotein 41 antibody does not impair the efficacy or safety of enfuvirtide. 

    2003  J Infect Dis 188: 977-85       
    Ruiz L, Ribera E, Bonjoch A, Romeu J, Martinez-Picado J, Paredes R, Diaz M, Marfil S, Negredo E, Garcia-Prado J, Tural C, Sirera G, Clotet B. 
    Role of structured treatment interruption before a 5-drug salvage antiretroviral regimen: the Retrogene Study. 

    2003  J Int Assoc Physicians AIDS Care (Chic Ill). 2003 Apr-Jun;2(2): 56-8.       
    D Fuster , B Clotet 
    Chronic HCV infection in HIV-positive patients: A new challenge 

    2003  J Postgrad Med , 49 : 39-49       
    R Paredes , J Muñoz , I Diaz , P Domingo , M Guigui , B Clotet 
    Leishmaniasis in HIV Infection 

    2003  J Postgrad Med 49: 39-49       
    Paredes, R., Munoz, J., Diaz, I., Domingo, P., Gurgui, M., Clotet, B. 
    Leishmaniasis in HIV infection 

    2003  J Viral Hepat 10: 118-125       
    Tural C, Fuster D, Tor J, Ojanguren I, Sirera G, Ballesteros A, Lasanta JA, Planas R, Rey-Joly C, Clotet B.  
    Time on antiretroviral therapy is a protective factor for liver fibrosis in HIV and hepatitis C virus (HCV) co-infected patients. 

    2003  J Virol 77: 4389-4395       
    Llano A, Barretina J, Gutierrez A, Clotet B, Este JA. 
    Interleukin-7-dependent production of RANTES that correlates with human immunodeficiency virus disease progression. 

    2003  JIAPAC , 9 : 145-165       
    C R Fumaz , B Clotet 
    Assessment of changes in adherence and quality of life after the simplification of antiretroviral treatment 

    2003  N Engl J Med , 348 : 2186-2195       
    A Lazzarin , B clotet , D Cooper , J Reynes , K Arastej , M Nelson , C Katlama , H J Setllbrink , J F Delfraissy , J Lange , L Huson , R DeMasi , C Wat , J Delehanty , C Drobnes , M Salgo ,  
    Enfuvirtide combined with an antiretroviral optimised background (OB) regimen in highly experienced HIV-1 patients: week 24 efficacy results of a Phase III randomized trial in Europe and Australia 

    2003  N Engl J Med 348:2186-95       
    A Lazzarin, B Clotet, D Cooper,J Reynes, K Arastéh, M Nelson, C Katlama, H-J. Stellbrink, J-F. Delfraissy, J. Lange, L. Huson, R. DeMasi, C. Wat, J. Delehanty, C. Drobnes, M. Salgo, for the TORO 2 Study Group 
    Efficacy of Enfuvirtide in Patients Infected with Drug-Resistant HIV-1 in Europe and Australia 

    2003  The Journal of Infectious Diseases, 188:977-85       
    L Ruiz, E Ribera, A Bonjoch, J Romeu, J Martinez-Picado, R Paredes, M Diaz, S Marfil, E Negredo, J Garcia-Prado, C Tural, G Sirera, and B Clotet 
    Role of Structured Treatment Interruption before a 5-Drug Salvage Antiretroviral Regimen: The Retrogene Study 

    2003  Top HIV Med 11: 150-154       
    Hirsch, M. S., Brun-Vezinet, F., Clotet, B., Conway, B., Kuritzkes, D. R., D'Aquila, R. T., Demeter, L. M., Hammer, S. M., Johnson, V. A., Loveday, C., Mellors, J. W., Richman, D. D. 
    Questions to and Answers from the International AIDS Society-USA Resistance Testing Guidelines Panel 

    2003  Top HIV Med 11: 215-21       
    Johnson VA, Brun-Vezinet F, Clotet B, Conway B, D'Aquila RT, Demeter LM, Kuritzkes DR, Pillay D, Schapiro JM, Telenti A, Richman DD; International AIDS Society-USA Drug Resistance Mutations Group. 
    Drug resistance mutations in HIV-1. 

    2003  Topics in HIV Medicine 11: 92-96       
    D'Aquila RT, Schapiro JM, Brun-Vezinet F, Clotet B, Conway B, Demeter LM, Grant RM, Johnson VA, Kuritzkes DR, Loveday C, Shafer RW, Richman DD. 
    Drug resistance mutations in HIV-1 

    2003  Topics in HIV Medicine 11 (6): 215-221       
    V A Johnson , F Brunt-Vezinet , B Clotet , B Conway , R D'Aquila , L Demeter , D Kuritzkes , D Pilay , J Schapiro , A Telenti , D Richman 
    Drug Resistance mutations in HIV-1 

    2003  VIH: I+T 8 ; 1 : 12       
    B Clotet 
    Experiencias en rescate, "naive" y simplificación 

    2003  Virology 305:318-329       
    Blanco J, Barretina J, Ferri KF, Jacotot E, Gutierrez A, Armand-Ugon M, Cabrera C, Kroemer G, Clotet B, Este JA.  
    Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events. 

    2002  AIDS , 16: 1 - 9       
    J García-Prado , T Wrin , J Beauchaine , L Ruiz , C J Petropoulos , B Clotet , R D'Aquila , J Martínez-Picado 
    Amprenavir resistant mutants show reduced viral fitness and cross-resistance to lopinavir 

    2002  AIDS 16 (12) : 1663-1671       
    A Mocroft , R Brettle , O Kirk , A Blaxhult , J M Parkin , F Antunes , P Francioli , A D'Arminio Monforte , Z Fox , J D Lundgren , EuroSIDA study group 
    Changes in the cause of death among HIV positive subjects across Europe: results from the EuroSIDA study 

    2002  AIDS 16: 1009-1017       
    Prado JG, Wrin T, Beauchaine J, Ruiz L, Petropoulos CJ, Frost SDW, Clotet B, D'Aquila RT and Martinez-Picado J 
    Amprenavir-resistant HIV-1 exhibits lopinavir cross-resistance and reduced replication capacity 

    2002  AIDS 16: 1383-1389       
    Negredo E, Ribalta J, Paredes R, Ferre R, Sirera G, Ruiz L, Salazar J, Reiss P, Masana L, Clotet B.  
    Reversal of atherogenic lipoprotein profile in HIV-1 infected patients with lipodystrophy after replacing protease inhibitors by nevirapine.  

    2002  AIDS 16:209-218       
    Tural C, Ruiz L, Holtzer C, Schapiro J, Viciana P, Gonzalez J, Domingo P, Boucher C, Rey-Joly C, Clotet B, and the Havana Study Group 
    Clinical utility of HIV-1 genotyping and expert advice: the Havana trial 

    2002  AIDS 16:2385-2390.       
    Martinez MA, Gutierrez A, Armand-Ugon M, Blanco J, Parera M, Gomez J, Clotet B, Este JA. 
    Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. 

    2002  AIDS 16:895-899       
    Martinez-Picado J, Morales-Lopetegi K, Wrin T, Prado JG, Frost S, Petropoulos CJ, Clotet B and Ruiz L 
    Selection of drug-resistant HIV-1 mutants in response to repeated structured treatment interruptions 

    2002  AIDS Res Hum Retroviruses 18:27-38       
    Blanco J, Barretina J, Gutierrez A, Armand-Ugon M, Cabrera C, Clotet B, and Esté JA 
    Preferential Attachment of HIV Particles to Activated and CD45RO+CD4+ T Cells 

    2002  AIDS Rev 4:36-40       
    Paredes R, Lopez Benaldo de Quiros JC, Fernandez-Cruz E, Clotet B, Lane HC.  
    The potential role of interleukin-2 in patients with HIV infection.  

    2002  Antivir Ther 7:21-30       
    Mocroft A, Phillips AN, Friis-Moller N, Colebunders R, Johnson AM, Hirschel B, Saint-Marc T, Staub T, Clotet B, Lundgren JD; EuroSIDA study group.  
    Response to antiretroviral therapy among patients exposed to three classes of antiretrovirals: results from the EuroSIDA study.  

    2002  Antiviral Res 53: 1-8       
    Cabrera, C., Gutierrez, A., Barretina, J., Blanco, J., Litovchick, A., Lapidot, A., Clotet, B., Este, J. A. 
    Anti-HIV activity of a novel aminoglycoside-arginine conjugate 

    2002  Butlletí del medicament , 4 : 19       
    N Rudi , X Bonafont , J Costa , P Salva , C Tural , B Clotet , C Rodrigo 
    Recomanacions per a evitar interaccions amb els antiretrovirals 

    2002  Clin Infect Dis 34:504-10       
    Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppression.  
    Negredo E, Cruz L, Paredes R, Ruiz L, Fumaz CR, Bonjoch A, Gel S, Tuldra A, Balague M, Johnston S, Arno A, Jou A, Tural C, Sirera G, Romeu J, Clotet B.  

    2002  Enferm Infecc Microbiol Clin 20 (6): 244-303       
    R Rubio , J Berenguer , J M Miró , A Antela , J A Iribarren , J Gonzalez , S Moreno , J Arrizabalaga , B Clotet , J M Gatell , F Laguna , E Martínez , F Parras , J M Santamaría , M Tuset , P Viciana por el GESIDA , el CAC del Plan Navional sobre el SIDA del Ministerio de Sanidad y Consumo 
    Recomendaciones del GESIDA/Plan Nacional sobre el SIDA respecto al tratamiento antiretroviral en pacientes adultos infectados por el virus de la inmunodeficiencia humana en el año 2002 

    2002  Enferm Infecc Microbiol Clin 20 Suppl 2:68-73.       
    Garcia F, Clotet B, Moreno S, Lopez Bernaldo De Quiros JC, Gatell JM.  
    Treatment interruptions in clinical practice 

    2002  Enferm Infecc Microbiol Clin 20: 244-303       
    Rubio R, Berenguer J, Miro JM, Antela A, Iribarren JA, Gonzalez J, Guerra L, Moreno S, Arrizabalaga J, Clotet B, Gatell JM, Laguna F, Martinez E, Parras F, Santamaria JM, Tuset M, Viciana P.  
    [Spanish GESIDA/National AIDS Plan Recommendations for Antiretroviral Therapy in HIV-infected Adults in the year 2002]  

    2002  Epidemiol Infect 129:325-33.       
    Egea JM, Muga R, Sirera G, Clotet B, Tor J, Ardevol M, Rey-Joly C, Munoz A.  
    Initiation, changes in use and effectiveness of highly active anti-retroviral therapy in a cohort of injecting drug users. 

    2002  HIV Clin Trials 2002;3(4):316-323       
    B Clotet, L Ruiz, J Martinez-Picado, E Negredo, A Hill, M Popescu 
    Prevalence of HIV Protease Mutations on Failure of Nelfinavir-Containing HAART: A Retrospective Analysis of Four Clinical Studies and Two Observational Cohorts 

    2002  Int J Infect Dis 6:17-22       
    Pedro-Botet ML, Modol JM, Valles X, Romeu J, Sopena N, Gimenez M, Tor J, Clotet B, Sabria M.  
    Changes in bloodstream infections in HIV-positive patients in a university hospital in Spain (1995-1997). 

    2002  J Acquir Immune Defic Syndr 29:244-253       
    Fumaz CR, Tuldra A, Ferrer MJ, Paredes R, Bonjoch A, Jou T, Negredo Romeu J, Sirera G, Tural C, and Clotet B. 
    Quality of Life, Emotional Status, and Adherence of HIV-1–Infected Patients Treated With Efavirenz Versus Protease Inhibitor–Containing Regimens 

    2002  J Clin Microbiol 40:3865-6.       
    Gallego O, Ruiz L, Vallejo A, Clotet B, Leal M, Soriano V. 
    Rate of Virological Treatment Failure and Frequencies of Drug Resistance Genotypes among Human Immunodeficiency Virus-Positive Subjects on Antiretroviral Therapy in Spain.  

    2002  J Infect Dis 186:189-97       
    Miller V, Phillips AN, Clotet B, Mocroft A, Ledergerber B, Kirk O, Ormaasen V, Gargalianos-Kakolyris P, Vella S, Lundgren JD.  
    Association of virus load, CD4 cell count, and treatment with clinical progression in human immunodeficiency virus-infected patients with very low CD4 cell counts.  

    2002  J Virol 76: 968-979       
    Frost SDW, Martinez-Picado J, Ruiz L, Clotet B, and Leigh Brown AJ 
    Viral Dynamics during Structured Treatment Interruptions of Chronic Human Immunodeficiency Virus Type 1 Infection 

    2002  J Virol 76:10546-10552       
    ME Quinones-Mateu,M Tadele, M Parera, A Mas, J Weber,HR Rangel, B Chakraborty, B Clotet, E Domingo, L Menendez-Arias, MA Martinez 
    Insertions in the Reverse Transcriptase Increase both Drug Resistance and Viral Fitness in a Human Immunodeficiency Virus Type 1 Isolate Harboring the Multi-Nucleoside Reverse Transcriptase Inhibitor Resistance 69 Insertion Complex Mutation 

    2002  J Virol 76:12344-12348       
    J Martinez-Picado, SDW Frost, N Izquierdo, K Morales-Lopetegi, S Marfil, T Puig, C Cabrera, B Clotet, L Ruiz 
    Viral Evolution during Structured Treatment Interruptions in Chronically Human Immunodeficiency Virus-Infected Individuals 

    2002  Top HIV Med 10: 21-25       
    D'Aquila RT, Schapiro JM, Brun-Vezinet F, Clotet B, Conway B, Demeter LM, Grant RM, Johnson VA, Kuritzkes DR, Loveday C, Shafer RW, Richman DD; International AIDS Society-USA. 
    Drug Resistance Mutations in HIV-1. 

    2002  Topics in HIV Medicine 10 (2) : 11-15       
    R D'Aquila , J M Schapiro , F Brun-Vézinet , B Clotet , B Conway , L Demeter , R Grant , V A Johnson , D Kuritkes , C Loveday , R Shafer , D D Richman 
    Drug Resistance mutations in HIV-1 

    2002  Trends Immunol 23: 559-561       
    Martínez MA, Clotet B and Esté JA 
    RNA interference of HIV replication 

    2002  Virology 300:71-8       
    Cabana M, Fernandez G, Parera M, Clotet B, Martinez MA. 
    Catalytic efficiency and phenotype of HIV-1 proteases encoding single critical resistance substitutions.  

    2002  Virology, 300 : 71-78       
    M Cabana , G Fernandez , M Parera , B Clotet , M A Martínez 
    Proteolytic efficiency and drug susceptibility of HIV-1 proteases carrying single critical substitutions in the development of PI resistances 

    2001  AIDS 25, 15 (8) : 999 - 1008       
    O Kirk , A Mocroft , C Pradier , J N Bruun , R Hemmer , B Clotet , V Miller , J P Viard , A Philips , J D Lundgren , for the EuroSIDA study group.  
    Clinical outcome among HIV-infected patients starting saquinavir hard gel compared to ritonavir or indinavir.  

    2001  AIDS , 15 : 2407-2414       
    M Van der Valk , J J Kastelein , R L Murphy , F Van Leth , C Katlama , A Horban , M Glesby , G Behrens , B Clotet , R K Stellato , H Molhuizen , P Reiss on behalf of the Atlantic Study Team 
    Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an antiatherogenic lipid profile 

    2001  AIDS 15 ; 15 (9) : F19 -27       
    L Ruiz , G Carcelain , J Martínez-Picado , S Frost , S Marfil , R Paredes , J Romeu , E Ferrer , K Morales-Lopetegi , M K Zayat , B Autran , B Clotet 
    HIV dynamics and T-cell immunity after three structured treatment interruptions in chronic HIV-1 infection.  

    2001  AIDS 15: 1890-1892 [Research letter]       
    Llano, A., Barretina, J., Blanco, J., Gutierrez, A., Clotet, B., and Este, J. A. 
    Stromal-cell-derived factor 1 prevents the emergence of the syncytium- inducing phenotype of HIV-1 in vivo.  

    2001  AIDS 15: 1894-1896 [Research letter]       
    Gallego, O., Ruiz, L., Vallejo, A., Ferrer, E., Rubio, A., Clotet, B., Leal, M., and Soriano, V.:  
    Changes in the rate of genotypic resistance to antiretroviral drugs in Spain 

    2001  AIDS 15: 1904-1906 [Research letter]       
    Tuldra, A., Fumaz, C. R., Ferrer, M. J., Paredes, R., Romeu, J., Ruiz, L., Bayes, R., and Clotet, B.:  
    Psychological impact of structured treatment interruptions in patients with prolonged undetectable HIV-1 viral loads.  

    2001  AIDS 15: 2407-14       
    van der Valk M, Kastelein JJ, Murphy RL, van Leth F, Katlama C, Horban A, Glesby M, Behrens G, Clotet B, Stellato RK, Molhuizen HO, Reiss P; Atlantic Study Team. 
    Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile. 

    2001  AIDS 15: 999-1008.       
    Kirk, O., Mocroft, A., Pradier, C., Bruun, J. N., Hemmer, R., Clotet, B., Miller, V., Viard, J. P., Phillips, A. N., and Lundgren, J. D. 
    Clinical outcome among HIV-infected patients starting saquinavir hard gel compared to ritonavir or indinavir.  

    2001  AIDS 15: F19-27       
    Ruiz, L., Carcelain, G., Martinez-Picado, J., Frost, S., Marfil, S., Paredes, R., Romeu, J., Ferrer, E., Morales-Lopetegi, K., Autran, B., and Clotet, B 
    HIV dynamics and T-cell immunity after three structured treatment interruptions in chronic HIV-1 infection.  

    2001  AIDS 26; 15 (2): 201-209       
    A Mocroft , A N Phillips , V Miller , J Gatell , J van Lunzen , J M Parkin , R Weber , B Roge , A Lazzarin , J D Lundgren , EuroSIDA study group  
    The use of and response to second-line protease inhibitor regimens: results from the EuroSIDA study.  

    2001  AIDS 28; 15 (14) : 1890-1892       
    A Llano , J Barretina , J Blanco , A Gutierrez , B Clotet , J A Esté 
    Stromal-cell-derived factor 1 prevents the emergence of the syncytium-inducing phenotype of HIV-1 in vivo.  

    2001  AIDS 28;15(14): 1890-1892       
    A Llano , J Barretina , J Blanco , A Gutierrez , B Clotet , J A Esté 
    Stromal-cell-derived factor 1 prevents the emergence of the syncytium-inducing phenotype of HIV-1 in vivo 

    2001  AIDS 5 ; 15 (1): 23-31       
    M Jouan , M Saves , R Tubiana , G Carcelain , N Cassoux , C Aubron-Olivier , A M fillet , M Nciri , B Senechal , C Tural , S Lasry , B Autran , C Katlama, for the RESTIMOP study team. 
    Discontinuation of maintenance therapy for cytomegalovirus retinitis in HIV-infected patients receiving highly active antiretroviral therapy 

    2001  Antivir Ther 6 (1) : 21-39       
    A M Vandamme , F Houyez , D Banhegyi , B Clotet , G de Schrijver , K de Smet , WW Hall , R Harrigan , N Hellmann , K Hertogs , C Holtzer , B Larder , D Pillay , E Race , J C Schmit , R Schuurman , E Shulse , A Sonnerborg , V Miller 
    Laboratory guidelines for the practical use of HIV drug resistance tests in patient follow-up 

    2001  Antivir Ther 6: 21-39.       
    Vandamme, A. M., Houyez, F., Banhegyi, D., Clotet, B., De Schrijver, G., De Smet, K. A., Hall, W. W., Harrigan, R., Hellmann, N., Hertogs, K., Holtzer, C., Larder, B., Pillay, D., Race, E., Schmit, J. C., Schuurman, R., Schulse, E., Sonnerborg, A., and Miller, V. 
    Laboratory guidelines for the practical use of HIV drug resistance tests in patient follow-up.  

    2001  Enferm Infecc Microbiol Clin 19 : 34-41       
    B Clotet , J Martínez-Picado , J Arrizabalaga , L Ruiz 
    Resistance to protease inhibitors 

    2001  Enferm Infecc Microbiol Clin 19: 34-41.       
    Clotet, B., Martinez-Picado, J., Arrizabalaga, J., and Ruiz, L.:  
    Resistance to protease inhibitors 

    2001  Enferm Infecc Microbiol Clin 19: 47-52.       
    Antela, A., Iribarren, J. A., Clotet, B., and Guerra, L. 
    Consensus documents and clinical guidelines on resistance to antiretroviral agents 

    2001  Enferm Infecc Microbiol Clin 19: 53-60.       
    Gatell, J. M., Blanco, J. L., Alcami, J., Antela, A., Arrizabalaga, J., Casado, J. L., Clotet, B., Delgado, R., Erice, A., Guerra, L., Guerrero, A., Iribarren, J. A., Leal, M., Lopez, J. C., Menendez-Arias, L., Miro, J. M., Moreno, S., Perez, J. L., Pumarola, T., Rubio, R., Ruiz, L., Santamaria, J. M., Soriano, V., Telenti, A., and Viciana, P. 
    GESIDA Consensus document on the use of resistance studies in clinical practice 

    2001  HIV Med. 2:27-34.       
    Katlama C, Clotet B, Plettenberg A, Jost J, Arasteh K, Bernasconi E, Jeantils V, Cutrell A, Stone C, Purdon S; CNA3002 European Study Team. 
    Intensification of stable background therapy with abacavir in antiretroviral therapy experienced patients: 48-week data from a randomized, double-blind trial. 

    2001  Intervirology 44 (6): 339-343       
    C Briones , A Mas , M Pérez-Olmesa , L Ruiz , B Clotet 
    Prevalence and genetic heterogeneity of the reverse transcriptase T69S-S-X insertion in pretreated HIV-infected patients 

    2001  J Acquir Immune Defic Syndr 27: 229-236.       
    Ruiz, L., Negredo, E., Domingo, P., Paredes, R., Francia, E., Balague, M., Gel, S., Bonjoch, A., Fumaz, C. R., Johnston, S., Romeu, J., Lange, J., and Clotet, B. 
    Antiretroviral treatment simplification with nevirapine in protease inhibitor-experienced patients with hiv-associated lipodystrophy: 1- year prospective follow-up of a multicenter, randomized, controlled study.  

    2001  J Med Virol 63: 85-87       
    Perez-Olmeda, M., Del Romero, J., Rubio, A., Ruiz, L., Rodriguez, C., Leal, M., Clotet, B., and Soriano, V. 
    Primary HIV-1 drug resistance in Spain before and after the introduction of protease inhibitors. 

    2001  J Rheumatol 28 (4) : 802-804       
    E Casado , A Olivé , S Holgado , R Perez-Andrés , J Romeu, J C Lorenzo , B Clotet , X Tena 
    Musculoskeletal manifestations in patients positive for human immunodeficiency virus: correlation with CD4 count.  

    2001  J Rheumatol 28: 802-804       
    Casado, E., Olive, A., Holgado, S., Perez-Andres, R., Romeu, J., Lorenzo, J. C., Clotet, B., and Tena, X. 
    Musculoskeletal manifestations in patients positive for human immunodeficiency virus: correlation with CD4 count. 

    2001  J Virol 75: 10319-10325.       
    Llano, A., Barretina, J., Gutierrez, A., Blanco, J., Cabrera, C., Clotet, B., and Este, J. A.: 
    Interleukin-7 in plasma correlates with CD4 T-cell depletion and may be associated with emergence of syncytium-inducing variants in human immunodeficiency virus type 1-positive individuals.  

    2001  Revista de la Reial Acacèmia de Medicina de Catalunya vol.16 , num.3       
    B Clotet 
    Reptes de la SIDA en el nou mil·leni 

    2001  Virology 282: 1-5       
    Ibanez, A., Clotet, B., and Martinez, M. A. 
    Absence of genetic diversity reduction in the HIV-1 integrated proviral LTR sequence population during successful combination therapy.  

    2001  Virology 285: 356-365       
    Blanco, J., Barretina, J., Cabrera, C., Gutierrez, A., Clotet, B., and Este, J. A. 
    CD4+ and CD8+ T cell death during human immunodeficiency virus infection in vitro.  

    2000  AIDS 10 ; 14 (4) : 397 -403       
    L Ruiz , J Martínez-Picado , J Romeu , R Paredes , E Negredo , C Tural , B Clotet 
    Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression.  

    2000  AIDS 10; 14 (16): 2485-2494       
    F García , H Knobel , M A Sambeat , J Arrizabalaga , M Aranda , J Romeu , D Dalmau , F Segura , J L Gómez-Sirvent , E Ferrer , A Cruceta , T Gallart , T Pumarola , J M Miró , J M Gatell , Spanish Scan Study Group 
    Comparison of twice-daily stavudine plus once- or twice-daily didanosine and nevirapine in early stages of HIV infection: the scan study.  

    2000  AIDS 14: 2857-2867.       
    Miller, V., Sabin, C., Hertogs, K., Bloor, S., Martinez-Picado, J., D'Aquila, R., Larder, B., Lutz, T., Gute, P., Weidmann, E., Rabenau, H., Phillips, A., and Staszewski, S.:  
    Virological and immunological effects of treatment interruptions in HIV- 1 infected patients with treatment failure.  

    2000  AIDS 14: 397-403.       
    L Ruiz , J Martínez-Picado, J Romeu , R Paredes , M K Zayat , S Marfil , E Negredo , G Sirera , C Tural , B Clotet  
    Structured treatment interruption in chronically HIV-1 infected patients after long-term viral suppression.  

    2000  AIDS 14: 469-471.       
    Van Laethem, K., Witvrouw, M., Balzarini, J., Schmit, J. C., Sprecher, S., Hermans, P., Leal, M., Harrer, T., Ruiz, L., Clotet, B., Van Ranst, M., Desmyter, J., De Clercq, E., and Vandamme, A. M.:  
    Patient HIV-1 strains carrying the multiple nucleoside resistance mutations are cross-resistant to abacavir.  

    2000  AIDS 14: 727-732.       
    Puig, T., Perez-Olmeda, M., Rubio, A., Ruiz, L., Briones, C., Franco, J. M., Gomez-Cano, M., Stuyver, L., Zamora, L., Alvarez, C., Leal, M., Clotet, B., and Soriano, V.:  
    Prevalence of genotypic resistance to nucleoside analogues and protease inhibitors in Spain. The ERASE-2 Study Group.  

    2000  AIDS 14: 781-789.       
    Katlama, C., Clotet, B., Plettenberg, A., Jost, J., Arasteh, K., Bernasconi, E., Jeantils, V., Cutrell, A., Stone, C., Ait-Khaled, M., and Purdon, S.:  
    The role of abacavir (ABC, 1592) in antiretroviral therapy-experienced patients: results from a randomized, double-blind, trial. CNA3002 European Study Team.  

    2000  AIDS 14: F1-7.       
    Casado, J. L., Hertogs, K., Ruiz, L., Dronda, F., Van Cauwenberge, A., Arno, A., Garcia-Arata, I., Bloor, S., Bonjoch, A., Blazquez, J., Clotet, B., and Larder, B.:  
    Non-nucleoside reverse transcriptase inhibitor resistance among patients failing a nevirapine plus protease inhibitor-containing regimen.  

    2000  AIDS Res Hum Retroviruses 10; 16 (9) : 825 - 833       
    K Van Laethem , J C Schmit , H Pelemans , J Balzarini , M Witvrouw , M J Perez-Perez ,M J Camarasa , R M Esnouf , S Aquaro , A Cenci , C F Perno , P Hermans , S Sprecher , L Ruiz , B Clotet , Van Wijngaerden , Van Ranst , J Desmyter , E De Clercq , A M Vandamme  
    Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients.  

    2000  AIDS Res Hum Retroviruses 16: 529-537.       
    Van Vaerenbergh, K., Van Laethem, K., Van Wijngaerden, E., Schmit, J. C., Schneider, F., Ruiz, L., Clotet, B., Verhofstede, C., Van Wanzeele, F., Muyldermans, G., Simons, P., Stuyver, L., Hermans, P., Evans, C., De Clercq, E., Desmyter, J., and Vandamme, A. M.:  
    Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.  

    2000  AIDS Res Hum Retroviruses 16: 627-634.       
    Cabrera, C., Gutierrez, A., Blanco, J., Barretina, J., Litovchick, A., Lapidot, A., Evdokimov, A. G., Clotet, B., and Este, J. A.:  
    Anti-human immunodeficiency virus activity of novel aminoglycoside- arginine conjugates at early stages of infection.  

    2000  AIDS Res Hum Retroviruses 16: 825-833.       
    Van Laethem, K., Schmit, J. C., Pelemans, H., Balzarini, J., Witvrouw, M., Perez-Perez, M. J., Camarasa, M. J., Esnouf, R. M., Aquaro, S., Cenci, A., Perno, C. F., Hermans, P., Sprecher, S., Ruiz, L., Clotet, B., Van Wijngaerden, E., Van Ranst, M., Desmyter, J., De Clercq, E., and Vandamme, A. M.:  
    Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino- 1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO- inexperienced HIV patients.  

    2000  AM J Respir Crit Care Med : 162 : 865-872       
    O Kirk , J M Gatell , A Mocroft , C Pedersen , R Proenca , R P Brettle , S E Barton , P Sudre , A N Philips , J D Lundgren , for the EuroSIDA study group ( J gonzalez-Lahoz and R Polo , B Clotet , A Jou , C Tural , J Gatell , J Miró 
    Infections with Mycobacterium Tuberculosis and Mycobacterium avium among HIV-infected patients after the introduction of highly active antiretroviral therapy 

    2000  Antimicrob Agents Chemother , 44 (5) : 1132-1139       
    MA Martínez , M Cabana , M Parera , A Gutierrez , J A Esté , B Clotet  
    A bacteriophage lambda-based genetic screen for characterization of the activity and phenotype of the human immunodeficiency virus type 1 protease.  

    2000  Antimicrob Agents Chemother 44: 1132-1139.       
    Martinez, M. A., Cabana, M., Parera, M., Gutierrez, A., Este, J. A., and Clotet, B.:  
    A bacteriophage lambda-based genetic screen for characterization of the activity and phenotype of the human immunodeficiency virus type 1 protease.  

    2000  Antimicrob Agents Chemother 44: 2109-2117.       
    Van Vaerenbergh, K., Van Laethem, K., Albert, J., Boucher, C. A., Clotet, B., Floridia, M., Gerstoft, J., Hejdeman, B., Nielsen, C., Pannecouque, C., Perrin, L., Pirillo, M. F., Ruiz, L., Schmit, J. C., Schneider, F., Schoolmeester, A., Schuurman, R., Stellbrink, H. J., Stuyver, L., Van Lunzen, J., Van Remoortel, B., Van Wijngaerden, E., Vella, S., Witvrouw, M., Yerly, S., De Clercq, E., Destmyer, J., and Vandamme, A. M.:  
    Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues.  

    2000  Antimicrob Agents Chemother 44: 51-56.       
    Blanco, J., Barretina, J., Henson, G., Bridger, G., De Clercq, E., Clotet, B., and Este, J. A.:  
    The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface- expressed human immunodeficiency virus type 1 envelope-induced apoptosis.  

    2000  Antivir Ther 5: 107-112.       
    Mocroft, A., Miller, V., Chiesi, A., Blaxhult, A., Katlama, C., Clotet, B., Barton, S., and Lundgren, J. D.:  
    Virological failure among patients on HAART from across Europe: results from the EuroSIDA study.  

    2000  Antiviral Res 46: 157-170.       
    Gimenez-Barcons, M., Sanchez-Fueyo, A., Ampurdanes, S., Puig-Basagoiti, F., Guilera, M., Ibanez, A., Clotet, B., Martinez, M. A., Rodes, J., Saiz, J. C., and Sanchez-Tapias, J. M.:  
    Genetic evolution of GB virus C/hepatitis G virus (GBV-C/HGV) under interferon pressure.  

    2000  Arch Intern Med 160: 1123-1132.       
    Paredes, R., Mocroft, A., Kirk, O., Lazzarin, A., Barton, S. E., van Lunzen, J., Katzenstein, T. L., Antunes, F., Lundgren, J. D., and Clotet, B.:  
    Predictors of virological success and ensuing failure in HIV-positive patients starting highly active antiretroviral therapy in Europe: results from the EuroSIDA study.  

    2000  Arch Intern Med 24 , 160 (8) : 1123 - 1132       
    R Paredes , A Mocroft , O Kitk , A Lazzarin , S E Barton , J van Lunzen , T L Katzenstein , F Antunes , J D Lundgren , B Clotet , for the EuroSida Study group 
    Predictors of virological success and ensuing failure in HIV-positive patients starting highly active antiretroviral therapy in Europe: results from the EuroSIDA study 

    2000  Arch Intern Med 24 , 160 (8) : 1123-1132       
    R Paredes , A Mocroft , O kitk , A Lazzarin , S E Barton , J van Lunzen , T L Katzenstein , F Antunes , J D Lundgren , B Clotet , for the EuroSIDA Study group 
    Predictors of virological success and ensuing failure in HIV-positive patients starting highly active antiretroviral therapy in Europe: results from the EuroSIDA study.  

    2000  Enferm Infecc Microbiol Clin 18: 329-351.       
    Miro, J. M., Antela, A., Arrizabalaga, J., Clotet, B., Gatell, J. M., Guerra, L., Iribarren, J. A., Laguna, F., Moreno, S., Parras, F., Rubio, R., Santamaria, J. M., and Viciana, P.:  
    [Recommendation of GESIDA (AIDS Study Group)/National Plan on AIDS with respect to the anti-retroviral treatment in adult patients infected with the human immunodeficiency virus in the year 2000 (I)].  

    2000  Enferm Infecc Microbiol Clin 18: 396-412       
    Miro, J. M., Antela, A., Arrizabalaga, J., Clotet, B., Gatell, J. M., Guerra, L., Antonio Iribarren, J., Laguna, F., Moreno, S., Parras, F., Rubio, R., Santamaria, J. M., and Viciana, P.:  
    [Recommendations of GESIDA (Grupo de Estudio de SIDA)/National Plan on AIDS with respect to the anti-retroviral treatment in adult patients infected with the human immunodeficiency virus in the year 2000 (II)].  

    2000  Enfermedades Infeccioasa y Microbiología Clínica 18; 8 : 396-412       
    J M Miró , A Antela , J Arrizabalaga , B Clotet , J M Gatell , L Guerra , J A Iribarren , F Laguna , S Moreno , F Parras , R Rubio , J M Santamaría , P Viciana por el grupo GESIDA 
    Recomendaciones de GESIDA/Plan Nacional sobre el SIDA respecto al tratamiento antirretrovírico en pacientes adultos infectados por el virus de la immunodeficiencia humana en el siglo 2000 (II) 

    2000  Enfermedades Infecciosas y Microbiología Clínica , 18 ; 7 : 329-351       
    J M Miró , A Antela , J Arrizabalaga , B Clotet , J M Gatell , L Guerra , J A Irribarren , F Laguna , S Moreno , F Parras , R Rubio , J M Santamaría , P Viciana por el grupo GESIDA 
    Recomendaciones de GESIDA/Plan Nacional sobre el SIDA respecto el tratamiento antirretrovirico en pacientes adultos infectados por el virus de la immunodeficiencia humana en el siglo 2000 

    2000  J Acquir Immune Defic Syndr 23: 89-94.       
    Puig-Basagoiti, F., Cabana, M., Guilera, M., Gimenez-Barcons, M., Sirera, G., Tural, C., Clotet, B., Sanchez-Tapias, J. M., Rodes, J., Saiz, J. C., and Martinez, M. A.:  
    Prevalence and route of transmission of infection with a novel DNA virus (TTV), hepatitis C virus, and hepatitis G virus in patients infected with HIV.  

    2000  J Acquir Immune Defic Syndr 25: 221-228.       
    Tuldra, A., Fumaz, C. R., Ferrer, M. J., Bayes, R., Arno, A., Balague, M., Bonjoch, A., Jou, A., Negredo, E., Paredes, R., Ruiz, L., Romeu, J., Sirera, G., Tural, C., Burger, D., and Clotet, B.:  
    Prospective randomized two-Arm controlled study to determine the efficacy of a specific intervention to improve long-term adherence to highly active antiretroviral therapy.  

    2000  J Acquir Immune Defic Syndr 25: 26-35.       
    Garcia, F., Alonso, M. M., Romeu, J., Knobel, H., Arrizabalaga, J., Ferrer, E., Dalmau, D., Ruiz, I., Vidal, F., Frances, A., Segura, F., Gomez-Sirvent, J. L., Cruceta, A., Clotet, B., Pumarola, T., Gallart, T., O'Brien, W. A., Miro, J. M., and Gatell, J. M.:  
    Comparison of immunologic restoration and virologic response in plasma, tonsillar tissue, and cerebrospinal fluid in HIV-1-infected patients treated with double versus triple antiretroviral therapy in very early stages: The Spanish EARTH-2 Study. Early Anti-Retroviral Therapy Study.  

    2000  J Gen Virol 81 Pt 1: 85-95.       
    Ibanez, A., Clotet, B., and Martinez, M. A.:  
    Human immunodeficiency virus type 1 population bottleneck during indinavir therapy causes a genetic drift in the env quasispecies.  

    2000  J of HIV Therapy 5 :3 ; 64-66       
    R Paredes , L Ruiz 
    Changing from a protease inhibitor to a non-nucleoside reverse transcriptase inhibitor 

    2000  JAMA 283: 2417-2426.       
    Hirsch, M. S., Brun-Vezinet, F., D'Aquila, R. T., Hammer, S. M., Johnson, V. A., Kuritzkes, D. R., Loveday, C., Mellors, J. W., Clotet, B., Conway, B., Demeter, L. M., Vella, S., Jacobsen, D. M., and Richman, D. D. 
    Antiretroviral drug resistance testing in adult HIV-1 infection: recommendations of an International AIDS Society-USA Panel.  

    2000  JANO Medicina y Humanidades , 13       
    J Martínez-Picado, B Clotet 
    Tratamiento de la infección por VIH: más allá de la carga viral 

    2000  JEM 192; 8 : 1-13       
    K F Ferry , E Jacotot , J Blanco , J A Esté , N Zamzami , S A Susuin , Z Xie , G Brothers , J Reed , J Penniger , G Kroemer 
    Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of Mitochondria and Caspases 

    2000  Rev Epidém et Santé Publ 48: 17-30       
    F Saillour-Glénisson , G Chene , L R Salmi , R Hafner , R Salamon et le groupe méta-analyse dapsone (G siera , B Clotet )  
    Effet de la dapsone sur la survie des patients infectés par le VIH : una méta-analyse des essais terminés 

    2000  Transfusion 40: 461-467.       
    Barretina, J., Blanco, J., Gutierrez, A., Puig, L., Altisent, C., Espanol, T., Caragol, I., Clotet, B., and Este, J. A.:  
    Evaluation of the putative role of C-C chemokines as protective factors of HIV-1 infection in seronegative hemophiliacs exposed to contaminated hemoderivatives.  

    1999  AIDS 13: 1045-1049.       
    Ibanez, A., Puig, T., Elias, J., Clotet, B., Ruiz, L., and Martinez, M. A.:  
    Quantification of integrated and total HIV-1 DNA after long-term highly active antiretroviral therapy in HIV-1-infected patients.  

    1999  AIDS 13: 1491-1496.       
    Garcia, F., Niebla, G., Romeu, J., Vidal, C., Plana, M., Ortega, M., Ruiz, L., Gallart, T., Clotet, B., Miro, J. M., Pumarola, T., and Gatell, J. M.:  
    Cerebrospinal fluid HIV-1 RNA levels in asymptomatic patients with early stage chronic HIV-1 infection: support for the hypothesis of local virus replication.  

    1999  AIDS 13: 1497-1502       
    J L Casado , J Arrizabalaga , M Montes , P Martí-Belda , C Tural , J Pinilla , C Gutierrez, J Portu , R Schuurman , K Aguirrebengoa for the CMV-AIDS Study Group 
    Incidence and risk factors for developing cytomegalovirus retinitis in HIV-infected patients receiving protease inhibitor therapy 

    1999  AIDS 13: 2377-2388.       
    Garcia, F., Romeu, J., Grau, I., Sambeat, M. A., Dalmau, D., Knobel, H., Gomez-Sirvent, J. L., Arrizabalaga, J., Cruceta, A., Clotet, B. G., Podzamczer, D., Pumarola, T., Gallart, T., O'Brien, W. A., Miro, J. M., and Gatell, J. M.:  
    A randomized study comparing triple versus double antiretroviral therapy or no treatment in HIV-1-infected patients in very early stage disease: the Spanish Earth-1 study.  

    1999  AIDS 13: 547-555.       
    Blanco, J., Cabrera, C., Jou, A., Ruiz, L., Clotet, B., and Este, J. A.:  
    Chemokine and chemokine receptor expression after combined anti-HIV-1 interleukin-2 therapy.  

    1999  AIDS 13: 909-917.       
    J Blanco , E Jacotot , C Cabrera , A Cardona , B Clotet, E De Clercq , J A Esté  
    The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling.  

    1999  AIDS 13: F1-8.       
    Ruiz, L., van Lunzen, J., Arno, A., Stellbrink, H. J., Schneider, C., Rull, M., Castella, E., Ojanguren, I., Richman, D. D., Clotet, B., Tenner-Racz, K., and Racz, P.:  
    Protease inhibitor-containing regimens compared with nucleoside analogues alone in the suppression of persistent HIV-1 replication in lymphoid tissue.  

    1999  AIDS Cyber Journal , 2 : 5       
    J A Esté , B Clotet 
    The HIV Coreceptors 

    1999  AIDS Cyber Journal , 2 : 674-681       
    M A Martínez , B Clotet 
    Clinical implications of the HIV-1 genetic variability 

    1999  AIDS Research and Human Retroviruses 15: 1535-1543.       
    Cabrera C, Witvrouw M, Gutierrez A, Clotet B, Kuipers ME, Swart PJ, Meijer DK, Desmyter J, De Clercq E, Este JA.  
    Resistance of the human immunodeficiency virus to the inhibitory action of negatively charged albumins on virus binding to CD4.  

    1999  Annals Internal Medicine , 130: 570-577       
    V Miller , A Mocroft , P Reiss , C Katlama , A Papadopoulos , T Katzenstein , J Van Lunzen , F Antunes , A Philips , J D Lundgren for the EuroSIDA Study Group. ( J Gonzalez-Lahoz and R Polo (Instituto Carlos III), B Clotet , A Jou , C Tural , J Gatell , J Miró 
    Relations among CD4 lymphocyte count Nadir , antiretroviral therapy, and HIV-1 disease progression: results from the EuroSIDA Study 

    1999  Antivir Ther 4: 45- 49.       
    Rubio, A., Gomez-Cano, M., Puig, T., Leal, M., Perez-Olmeda, M., Ruiz, L., Clotet, B., Rey, C., Zamora, L., Xaus, N., and Soriano, V.:  
    Presence of genotypic resistance in nucleoside analogue-treated HIV-1- infected patients with undetectable viral load.  

    1999  Antivir Ther 4: 123-124.       
    M Gomez-Cano, A Rubio, L Ruiz , M Perez-Olmeda , M Leal , B Clotet , V Soriano  
    Efficiency of drug resistance genotypic tests in specimens with low HIV viral load.  

    1999  Antivir Ther 4: 179-181       
    Perez-Olmeda M, Rubio A, Puig T, Gomez-Cano M, Ruiz L, Leal M, Clotet B, Soriano V. 
    Evolution of genotypic resistance to nucleoside analogues in patients receiving protease inhibitor-containing regimens. 

    1999  Arch Intern Med 159: 1376-1377.       
    Tuldra, A., Ferrer, M. J., Fumaz, C. R., Bayes, R., Paredes, R., Burger, D. M., and Clotet, B.:  
    Monitoring adherence to HIV therapy.  

    1999  Int J Clin Pract Suppl 103: 21-25.       
    Clotet, B.:  
    Efavirenz: resistance and cross-resistance.  

    1999  J Acquir Immune Defic Syndr 22: 132-138.       
    Paredes, R., Puig, T., Arno, A., Negredo, E., Balague, M., Bonjoch, A., Jou, A., Tuldra, A., Tural, C., Sirera, G., Veny, A., Romeu, J., Ruiz, L., and Clotet, B.:  
    High-dose saquinavir plus ritonavir: long-term efficacy in HIV-positive protease inhibitor-experienced patients and predictors of virologic response.  

    1999  J Infect Dis 180: 56-60.       
    Arno, A., Ruiz, L., Juan, M., Jou, A., Balague, M., Zayat, M. K., Marfil, S., Martinez-Picado, J., Martinez, M. A., Romeu, J., Pujol-Borrell, R., Lane, C., and Clotet, B.:  
    Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons with <=250/microL CD4 T cells and undetectable plasma virus load.  

    1999  J Med Virol 59: 480-490.       
    Cabana, M., Clotet, B., and Martinez, M. A.:  
    Emergence and genetic evolution of HIV-1 variants with mutations conferring resistance to multiple reverse transcriptase and protease inhibitors.  

    1999  J Virol 73: 5577-5585.       
    Este, J. A., Cabrera, C., Blanco, J., Gutierrez, A., Bridger, G., Henson, G., Clotet, B., Schols, D., and De Clercq, E.:  
    Shift of clinical human immunodeficiency virus type 1 isolates from X4 to R5 and prevention of emergence of the syncytium-inducing phenotype by blockade of CXCR4.  

    1999  JAIDS       
    F Puig , M Cabana , M Guilera , M Gimenez , G Sirera , C Tural , B Clotet , J Sánchez , J Rodés , J C Saiz , M A Martínez 
    Prevalence and route of Transmission of infection with a novel DNA virus (TTV) and Hepatitis G virus in patients infected with HIV 

    1999  JAMA       
    M Hirsch , B Vezinet , R D'Aquila , S Hammer , Johnson , Kuritzkes , Loveday , Mellors , B Clotet , B Conway , Demeter , S Vella , D Richman 
    Antiretroviral drug resistance testing in adult HIV-1 infection : Recommendations of an International AIDS Society - USA Panel 

    1999  JANO LVI, 1291 : 1028       
    B Clotet , R Paredes 
    Tratamiento del Sida y profilaxis de las infecciones asociadas en el año 2000 

    1999  Journal of virology , 73 , 7 : 5577-5585       
    J A Esté , C Cabrera , D Schols , J Blanco , A Gutierrez , G Bridger , G Henson , B Clotet , E De Clercq 
    Shift of X4 to R5 HIV from clinical isolates through blockade of the CXCR4 receptor by the bicyclam AMD3100 

    1999  Mol Pharmacol 55 : 67-73.       
    J A Esté , C Cabrera , E De Clercq , S Struyf , J Van Damme , G Bridger , R T Skerlj , M J Abrams, G Henson , A Gutierrez , B Clotet , D Schols  
    Activity of different bicyclam derivatives against human immunodeficiency virus depends on their interaction with the CXCR4 chemokine receptor.  

    1999  Scand J Infect Dis 31(1) : 37-42.       
    J Romeu , M Balague , L Ruiz , S Marfil , J M Gatell , T Puig , A Arno , C Tural , G Sirera , B Clotet  
    Short-term risk for AIDS-indicator diseases predicted by plasma HIV-1 RNA and CD4+ lymphocytes.  

    1999  The Lancet , 353 : 1293-1298       
    G J Weverling , A Mocroft , B Ledergerber , O Kirk , H Gonzales-Lahoz , A D'Arminio Monforte , R Proenca , A N Philips , J D Lundgren , P Reiss , for the EuroSIDA study group. (J Gonzalez-Lahoz and R Polo (Instituto Carlos III) B Clotet , A Jou , C Tural (Hospital Germans Trias i Pujol ) J Gatell and J Miró (Hospital Clinic de Barcelona) on behalf of Spanish centers 
    Discontinuation of Pneumocystis carinii pneumonia prophylaxis after the initiation of highly active antiretroviral therapy in HIV infection 

    1999  Transfusion, 40 (4) : 461 - 467       
    J Barretina , J Blanco , Ll Puig , C Altisent , T Español , I Caragol , B Clotet , J A Esté 
    Evaluation of the putative role of C-C chemokines as protective factors of HIV-1 infection in seronegative hemophiliacs exposed to contaminated hemoderivatives.  

    1999  Virology, 256 : 180-187.       
    M A Martínez , M Cabana , A Ibanez , B Clotet , A Arno , L Ruiz 
    Human immunodeficiency virus type 1 genetic evolution in patients with prolonged suppression of plasma viremia.  

    1999  Weekly highlights, 15 : 42 - 45       
    J A Esté 
    Retrovirus infections and antiviral research 

    1998  AIDS 12: 1015-1020.       
    Gomez-Cano, M., Rubio, A., Puig, T., Perez-Olmeda, M., Ruiz, L., Soriano, V., Pineda, J. A., Zamora, L., Xaus, N., Clotet, B., and Leal, M.:  
    Prevalence of genotypic resistance to nucleoside analogues in antiretroviral-naive and antiretroviral-experienced HIV-infected patients in Spain.  

    1998  AIDS 12: 1285-1289.       
    Vidal C, Garcia F, Romeu J, Ruiz L, Miro JM, Cruceta A, Soriano A, Pumarola T, Clotet B, Gatell JM.  
    Lack of evidence of a stable viral load set-point in early stage asymptomatic patients with chronic HIV-1 infection.  

    1998  AIDS 12: 2007-2015.       
    Schmit JC, Van Laethem K, Ruiz L, Hermans P, Sprecher S, Sonnerborg A, Leal M, Harrer T, Clotet B, Arendt V, Lissen E, Witvrouw M, Desmyter J, De Clercq E, Vandamme AM.  
    Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries.  

    1998  AIDS 12: 697-704.       
    Arno, A., Ruiz, L., Juan, M., Zayat, M. K., Puig, T., Balague, M., Romeu, J., Pujol, R., O'Brien, W. A., and Clotet, B.:  
    Impact on the immune system of undetectable plasma HIV-1 RNA for more than 2 years.  

    1998  Ann Rheum Dis, 57: 749.       
    Olive, A., Salavert, A., Manriquez, M., Clotet, B., and Moragas, A.:  
    Parotid lipomatosis in HIV positive patients: a new clinical disorder associated with protease inhibitors.  

    1998  Clin Infect Dis 26: 1368-1373.       
    Phillips, P., De Beule, K., Frechette, G., Tchamouroff, S., Vandercam, B., Weitner, L., Hoepelman, A., Stingl, G., and Clotet, B.:  
    A double-blind comparison of itraconazole oral solution and fluconazole capsules for the treatment of oropharyngeal candidiasis in patients with AIDS.  

    1998  Enferm Infecc Microbiol Clin 16: 374-376.       
    Moreno, S., Arrizabalaga, J., Gatell, J. M., Clotet, B., Aguirrebengoa, K., Antela, A., Iribarren, J. A., Laguna, F., Miro, J. M., Ocana, I., Rubio, R., Viciana, P., and Podzamczer, D.:  
    [Recommendations for antiretroviral treatment in 1998. AIDS Working Group of the Spanish Society for Infectious Diseases and Clinical Microbiology (SEIMC)].  

    1998  J Gen Virol       
    M Giménez-Barcons , A Sánchez-Fueyo , S Ampurdanés , F Puig , M Guilera , A Ibañez , B Clotet , M A Martínez , J Rodés , J C Saiz , J M Sánchez 
    Genetic evolution of hepatitis G virus/ GB virus C (HGV/GBV-C) under interferon pressure 

    1998  J Infect Dis 177: 1080-1083.       
    Tural, C., Romeu, J., Sirera, G., Andreu, D., Conejero, M., Ruiz, S., Jou, A., Bonjoch, A., Ruiz, L., Arno, A., and Clotet, B.:  
    Long-lasting remission of cytomegalovirus retinitis without maintenance therapy in human immunodeficiency virus-infected patients.  

    1998  J Int Assoc Physicians AIDS Care 4: 60-63.       
    Este, J. A. and Clotet, B.:  
    HIV phenotype & genotype data highlights Lake Maggiore meeting.  

    1998  J Med Virol 55: 293-299.       
    Ibanez, A., Gimenez-Barcons, M., Tajahuerce, A., Tural, C., Sirera, G., Clotet, B., Sanchez-Tapias, J. M., Rodes, J., Martinez, M. A., and Saiz, J. C.:  
    Prevalence and genotypes of GB virus C/hepatitis G virus (GBV-C/HGV) and hepatitis C virus among patients infected with human immunodeficiency virus: evidence of GBV-C/HGV sexual transmission.  

    1998  J Virol Methods 73: 77-82.       
    Schmit, J. C., Ruiz, L., Stuyver, L., Van Laethem, K., Vanderlinden, I., Puig, T., Rossau, R., Desmyter, J., De Clercq, E., Clotet, B., and Vandamme, A. M.:  
    Comparison of the LiPA HIV-1 RT test, selective PCR and direct solid phase sequencing for the detection of HIV-1 drug resistance mutations.  

    1998  JAMA 279: 1984-1991.       
    Hirsch, M. S., Conway, B., D'Aquila, R. T., Johnson, V. A., Brun-Vezinet, F., Clotet, B., Demeter, L. M., Hammer, S. M., Jacobsen, D. M., Kuritzkes, D. R., Loveday, C., Mellors, J. W., Vella, S., and Richman, D. D.:  
    Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management. International AIDS Society--USA Panel.  

    1998  Journal of Acquired Immune Deficiciency Syndromes 17: 239-244.       
    Phillips, A. N., Katlama, C., Barton, S., Vella, S., Blaxhult, A., Clotet, B., Goebel, F. D., Hirschel, B., Pedersen, C., and Lundgren, J. D.:  
    Survival in 2367 zidovudine-treated patients according to use of other nucleoside analogue drugs. The EuroSIDA Study Group.  

    1998  Journal of Acquired Immune Deficiciency Syndromes 19: 19-28.       
    Ruiz, L., Nijhuis, M., Boucher, C., Puig, T., Bonjoch, A., Martinez-Picado, J., Marfil, S., de Jong, D., Burger, D., Arno, A., Balague, M., and Clotet, B.:  
    Efficacy of adding indinavir to previous reverse transcriptase nucleoside analogues in relation to genotypic and phenotypic resistance development in advanced HIV-1-infected patients.  

    1998  Journal of Acquired Immune Deficiciency Syndromes 19: 55-60.       
    Vidal C, Garcia F, Gatell JM, Leal M, Clotet B, Pumarola T, Miro JM, Mallolas J, Ruiz L, Cruceta A, Tortajada C.  
    Predictive factors influencing peak viral load drop in response to nucleoside reverse transcriptase inhibitors in antiretroviral-naive HIV- 1-infected patients.  

    1998  Med Clin 110: 109-116.       
    Moreno, S., Arrizabalaga, J., Gatell, J. M., Clotet, B., Aguirrebengoa, K., Antela, A., Iribarren, J. A., Laguna, F., Miro, J. M., Ocana, I., Rubio, R., Viciana, P., and Podzamczer, D.:  
    [Recommendations on antiretroviral treatment. The AIDS Study Group of the Spanish Society of Infectious Diseases and Clinical Microbiology].  

    1998  Med Clin 110: 761-767.       
    Romeu, J., Balague, M., Ruiz, L., Marfil, S., Puig, T., Arno, A., Veny, A., Tural, C., Sirera, G., and Clotet, B.:  
    [Value of HIV-1 viral load and CD4 lymphocyte count as determinants of progression to AIDS and survival].  


     

     

     

     

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